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Sharad Chand
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences, Paneer, Nitte (Deemed to be University), Mangaluru- 575018.
Medicine & Pharmacology

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Assessment of Drug Utilization Pattern in Chronic Kidney Disease Patients in A Tertiary Care Hospital Based on Who Core Drug Use Indicators Sharad Chand; C. S Shastry
Journal of Global Pharma Technology Volume 11 Issue 09 (2019) September 2019
Publisher : Journal of Global Pharma Technology

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Abstract

Introduction: Chronic kidney disease (CKD) is defined as any decrease in the glomerular filtration rate (GFR) with an abnormality in the kidney structure or its function. CKD patients are presented with multiple co-morbidities and compromised pharmacokinetics resulting in compromised quality of life and considerable economic burden. Aim: To study the drug utilization pattern in Chronic Kidney Disease (CKD) patients by using the World Health Organization (WHO) core drug use indicators. Materials and Method: A prospective observational drug utilization study was carried out in out-patients of Department of Nephrology of Justice K S Hegde Charitable Hospital, Mangaluru, for period of 8 months. CKD patients with an age of 18 years and above were included with consent. Data was collected using data collection forms, patients case notes, prescriptions sheet and personal interviews. Result: A total of 256 patients were recruited. Of which, 192 (75%) patients were males and 64(25%) were females with a mean age of 54.5 years. Average consultation time was 6.5 minutes. A total of 1374 drugs were prescribed to these patients with an average of 5.3 drugs per prescription. The most common prescribed class of drugs were for the cardiovascular system (42.6%) followed by the hematopoietic system (16.7%). Further, 65% of the drugs were prescribed from the National list of essential medicines (NLEM) whereas 8.7% of drugs were prescribed by generic name. Conclusion:  Utilizing the WHO’s core drug use indicators in this special patient population will strengthen the current hospital drug use policies and improve the drug usage pattern, saving the precious life years and monetary resources.
Brown, White and Blue Bagging in Special Pharmacy: An Emerging Trend to Minimize Medication Error Sharad Chand
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

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Advancement in the sector of specialized pharmacy evolved a new concept of bagging system beyond the scope of traditional pharmacy service. Managed care organizations (MCOs) bring up the healthcare system in the network where the services are made available for the betterment of treatment and secure documentation system for reimbursement. Certain models namely brown bagging, white bagging, and blue bagging system are promising models for this system. These models generally cover expensive and high-risk medication to minimize the wastage and related drug related problems. In these models, all the prescribed medications reach to the health professionals, which meticulously review all the medications before its administration. This potential system has several advantages over the conventional pharmacy practices, despite several advantages many associated risk and disadvantages are equally challenging. But it can be concluded that benefits are outweighing the risk associated with these models, which may have more impact on patient wellbeing. Hence, this system of special pharmacy service can be recommended in the scope of hospital pharmacy and pharmacy practice.
Isoniazid Induced Psychosis Sharad Chand
Journal of Global Pharma Technology Volume 11 Issue 05 (2019) May 2019
Publisher : Journal of Global Pharma Technology

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Isoniazid (INH) is one of the primary drugs used in the treatment of Mycobacterium tuberculosis infection. The common side effects of INH are peripheral neuropathy, hepatitis, rashes. Rarely psychosis, convulsions, and even death have been reported on regular doses of this drug. We present a case of Isoniazid induced psychosis occurring in a 36-year-old female patient was admitted to the general medicine unit for tuberculosis. The case was analyzed for suspected ADR and found to be probable ADR of isoniazid. The drug was discontinued, and antitubercular therapy was changed to modified approach,i.e. (R- Rifampicin 450mg, I- Ethambutol 800mg, S-Streptomycin 750mg and O- Ofloxacin 400mg) which shows clinical improvement in the patient.
Co-Authors C. S Shastry