Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Journal of Global Pharma Technology
Entsar Jabbar Saheb
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Auto-antibodies Profile in Children Infected with Visceral Leishmaniasis Entsar Jabbar Saheb
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (408.557 KB)

Abstract

Visceral leishmaniasis (VL) is a parasitic infection caused by an intracellular growth of Leishmania spp. in macrophage cells. The autoimmune disorder is a condition takes place when the immune system produces antibodies which incorrectly attacked its own body tissues. VL has been involved as an effect or on the autoimmune aspect. This study was conducted to identify the auto antibodies profile in patients infected with VL.  The presences of auto antibodies in 21 Iraqi children infected with VL were tested for laboratory autoimmune aspect. The highest percentage of seropositive in Leishmania patients was observed for anti-ds DNA, anti-Mi-2, anti-Ku and anti-PCNA antibodies (90.5%, 90.5% , 90.5% and 61.9%) respectively, while the lowest percentage was recorded for anti-Histone, anti-R0(RPP), anti-SS-A/Ro 52, anti-Scl 70, anti-Jo-1 antibodies (4.8%) while the auto antibodies (anti-SmD1, anti-SS-A/Ro-60, anti-SS-B/La, anti-CENP, anti-U1snRNP, anti-AMA M2, anti-PM/Scl) showed different profiles in Leishmania patients. These results provide evidence that VL can have an effective role in the production of the auto antibodies.Keywords: Children, Leishmania spp, Visceral leishmaniasis, Auto antibodies.
Co-Authors