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Miad Hassan Jebur
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Medicine & Pharmacology

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Synthesis and Characterization of Some New Derivatives of Thiourea and Study of Their Biological Activity Miad Hassan Jebur
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

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Abstract

Some new derivatives of Suberyl Chloride  synthesized by reacting with ammonium  thiocyanate then the product is reacting with some amino acids to prepare thioureio-amino acid,  as well as react with two amino hetrocyclic compounds are 2-aminobenzo[d]thiozole-6-carboxylic acid and thiophen-2-amine to prepare thiourea derivatives. This reaction was checked by thin‐layer chromatography (TLC) method. All new compounds were characterized by melting points, elemental analysis, FT‐IR and 1H&13C-NMR. The antibacterial action of these derivatives was also determined as well as study three of these derivatives as anti-breast cancer. Keywords: Suberyl Chloride, thioureio-amino acid, antibacterial, thiourea derivatives, anti-breast cancer.
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