Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal Journal of Global Pharma Technology
Ali Hadi Mahdi
Unknown Affiliation
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Treatment of Children with Immune Thrombocytopenia by High Dose Intravenous Dexamethasone: A Window for Improvement Ali Hadi Mahdi
Journal of Global Pharma Technology Volume 09 Issue 12
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction Immune thrombocytopenia is a hematological disorder Characterized by platelet destruction caused by auto antibodies resulting in reduction in platelet count to lower than normal range and increased bleeding tendency. Corticosteroids are considered one of the most appropriate treatment options for pediatric ITP. Methods: In this study 16 pediatric patients with acute ITP had been enrolled to evaluate their response to high pulsed dose of dexamethasone given as a 4-day course every 14 days for 4 courses by measuring their platelet counts before and after each course and along 14 months after completing the 4 courses. Results: There was a significant (p<0.0001) increase in platelet count after each cycle in comparison with platelet count before the same cycle. All the patients, at the end of fourth cycle, showed either partial or complete response and no one showed minimal or no response. Conclusion: High dose dexamethasone can be proposed as a first-line treatment for children with ITP. Repeated cycles of therapy seem to be more efficient than only one cycle to achieve a long-term response. 
Co-Authors