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Jumana W. Ammar
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Medicine & Pharmacology

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Rapid Determination of Bi (III) and Al (III) in Pharmaceutical Formulations using Organic Reagent Spectrophotometrically Jumana W. Ammar
Journal of Global Pharma Technology Volume 12 Issue 02 (2020) Feb. 2020
Publisher : Journal of Global Pharma Technology

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Abstract

A new trend describes the development and validation of a simple, sensitive and selective spectrophotometric methods for the determination of Bi (III) and Al (III) in pharmaceutical formulations have been conducted. In this paper, 4-(4 acetamidophenylazo) pyrogallol was synthesized as a new organic compound, 4-APAP, by coupling pyrogallol with diazotized p- aminoacetanilide in medium of controlled pH. 4- APAP was characterized by techniques of FT-IR, H-NMR, GC-Mass, TG and DSC thermal analysis methods. Solvatochromic behavior in solvents of various polarities was also investigated.Keywords: Pharmaceutical applications, Pyrogallol, Bi (III), Al (III).
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