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Dhefaf H. Badri
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Medicine & Pharmacology

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Synthesis and Characterization of Heterocyclic Compounds and Polymers with Studying the Biological activity for some of them Dhefaf H. Badri
Journal of Global Pharma Technology Volume 11 Issue 07
Publisher : Journal of Global Pharma Technology

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Abstract

This paper deals with the preparation of new monomers and polymers which including heterocyclic unit. The diacid chlorides compounds [1-3] were prepared from the reaction of glutaric acid, adipic acid, terephthalic acid with thionyl chloride.  Succinic acid reacted with ethanol to produce compound [4]. Compound [4] reacted with hydrazine hydrate to obtain succinic hydrazide [5].Compound [5] reaction with CS2 and KOH in absolute ethanol to produce compound [6].The polymers [7-12] have been created by  reacting diacid chlorides compounds [1-3] with compound[5] or [6] in dry pyridine with some drops of DMF. The topology of produced compounds has characterized through their spectral and analytical data as in FT-IR spectra, Thermal analysis [DSC, TGA] and Antibacterial activity investigated using dual bacteria kinds.Keywords: Succinic hydrazides, Oxadiazole, Heterocyclic polymers.
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