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Safa S. Zayied
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Medicine & Pharmacology

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Separation with Determination Iron (III) and Paracetamol Drug via Onium System Safa S. Zayied
Journal of Global Pharma Technology Volume 11 Issue 2: 2019
Publisher : Journal of Global Pharma Technology

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Abstract

Onium technique used as sensitive method for extraction and determination Fe(III) by using paracetamol drug so determination this drug by using Fe(III) within a study for determination the optimum conditions appear onium species formed wave length for maximum absorbance is equal to λ max =247nm,  so this formation for stable onium species need existence 1.5 M HCl in aqueous solution and 1x10-4M paracetamol, with 15 minutes shaking time, also and in order to enhancement the extraction efficiency need operation existence 50% methanol and 0.1 M NaCl in the aqueous phase thermodynamic study shows the operation was endothermic with data equal to Δ Hex = 0. 0397  KJmol-1 , Δ G ex = -54.44 kJmol-1, Δ Sex =174.06 J mol-1k-1 , the study involved also organic solvent effect , interference and spectrophotometric determination of Fe3+ and drug paracetamol.Key words: Onium System, Iron (III), Paracetamol, Determination.
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