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Effect of hydrothermal time on the hydrochar characteristics of galam (Malaleuca leucadendra) bark and application tests as methylene blue adsorbent Sunardi Sunardi, Ph.D.; Risaldi Ridwan; Hanna Habibah; Desmalina Safitri; Utami Irawati
Jurnal Riset Industri Hasil Hutan Vol 14, No 2 (2022)
Publisher : Kementerian Perindustrian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24111/jrihh.v14i2.7964

Abstract

Production of galam wood produces bark waste that is disposed in around of the production site without processing. The use of galam bark waste is very necessary to reduce waste and its problems in the environment and optimize the potential of galam wood as a typical Kalimantan plant. In this research, modification of galam bark biomass (Malaleuca leucadendra) into hydrochar through a hydrothermal process with variations of hydrothermal time and its use for methylene blue adsorbent has been done. The hydrothermal process was carried out at the temperature of 200˚C for 3 hours, 6 hours, and 12 hours. The characterization of hydrochar substrate using FTIR (Fourier Transform Infrared Spectroscopy) showed the decrease in absorption intensity of 47% and a shift in several wavenumbers. The characterization using SEM (Scanning Electron Microscope) showed that there are morphological changes on the surface of the hydrochar become to more holes after the hydrothermal process. The optimum condition for adsorption occurred at pH 7 for 10 minutes. The adsorption capacity of methylene blue increased from 44.70 mg/g to 45.82, 46.17, and 46.90 mg/g after hydrothermal process. The results also showed that the adsorption followed the Freundlich isothrm which showed a tendency for multilayer interactions on the surface of the galam barks after the hydrothermal process.
Effect of Kelakai (Stenochlaena palutris) Extract on Organophosphate Pesticide Exposure: Cytotoxic Studies in Ovo and in Silico Nafisah Nafisah; Sarmila Sarmila; Hanna Habibah; Indah Saputri; Indah Setiawati; Noer Komari
Jurnal Sains dan Terapan Kimia Vol 17, No 2 (2023)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jstk.v17i2.14583

Abstract

Vegetable farmers in South Kalimantan use pesticides to protect crops from pests. The active ingredient of the pesticide has a broad toxic effect on target and non-target organisms. Continuous exposure to pesticides causes cancer. The plant of mantle (Stenochlaena palustris) is thought to have potential cytotoxic activity against cancer cell growth. The aim of this study was to examine the potential activity of chemical compounds in anaplastic lymphoma kinase (ALK) exposed to organophosphate pesticides in silico and in ovo. The in silico study used molecular docking and virtual screening methods. The methanol extract of malachite was obtained by maceration method. The in ovo study was carried out by injecting pesticide compounds and methanol extracts of methanol at doses of 0.5 and 1 ppm to free-range chicken eggs. The results of the in silico analysis showed that ethion and neophytadiene had the most negative G values, namely -8.62 kcal/mol and -8.39 kcal/mol, while the natural ligand 8 LY A 500 was -9.19 kcal/mol. The similarity of the type and number of residues in the binding complex between ethion and neophyadiene ligands with ALK protein indicates the potential for competition between ethion and neophyadiene when bound to ALK protein. Neofitadiene is suspected as a compound that has potential as anti-cancer by inhibiting the growth of ALK. Anchovy extract is considered to be able to slow down the rate of cell damage in chicken embryos caused by ethion with its inhibitory ability so that the cell surface is not damaged quickly.