H. A. Hassim, H. A.
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Histological changes of liver tissues and serobiochemical relation in does with pregnancy ketosis Azmi, Amirul Faiz Mohd; Ghani, A.A.A.; Saadan, A. S.; Mokrish, A.; Lai, K. S.; Zamri-Saad, M.; Zuki, A. B.; Hassim, H. A.
Jurnal Ilmu Ternak dan Veteriner Vol 21, No 2 (2016): JUNE 2016
Publisher : Indonesian Animal Sciences Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (53.569 KB) | DOI: 10.14334/jitv.v21i2.1392.x

Abstract

The histological changes of the liver in does with pregnancy ketosis were characterized. Twenty pregnant does at day 80 of pregnancy were used for this experiment. A total of 10 does were fed on grass (napier) and goat concentrate with water ad libitum consider as healthy pregnant goat, and another 10 ten were showed clinical and subclinical signs of ketosis consider as unhealthy pregnant doe. Liver biopsies were performed when clinical signs appear. Beta-Hydroxybutyrate (BHBA), free fatty acid (FFA), and glucose were dosed. Histological preparation revealed similar incidence and intensity of mild liver steatosis with lower cellular vacuolation in hepatocyte presence in healthy late pregnant does. Almost all of pregnant does with ketosis state (n=8/10) had large amount of small lipid droplets in almost every hepatocyte over the whole liver acinus with higher number of cellular vacuolation, and related with higher BHBA and FFA levels while low in glucose levels.Key Words: Beta-Hydroxybutyrate, Does, Free Fatty Acid, Liver Biopsies, Pregnancy Ketosis
A Comprehensive Meta-Analysis of Cassava Addition in a Buffalo Diet: In Vivo Investigations on Performance and Rumen Health Amirul, F. M. A.; Mazlan, N. A.; Sadarman, S.; Rusli, N. D.; Sholikin, M. M.; Irawan, A.; Febrina, D.; Qomariah, N.; Nurfitriani, R. A.; Aditya, S.; Jayanegara, A.; Saad, M. Z.; Adli, D. N.; Hassim, H. A.
Tropical Animal Science Journal Vol. 48 No. 4 (2025): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2025.48.4.298

Abstract

This meta-analysis compiles data on buffalo consumption of cassava as a feed ingredient to evaluate its impact on in vivo rumen fermentation, feed intake, nutrient intake, growth performance, digestibility, nitrogen metabolism, haematology, microbiology, and milk yield. A systematic search of Scopus and Web of Science identified 19 in vivo experiments. Cassava varieties were categorized as by-products, foliage, and roots, while buffaloes were stratified based on management system, breed, and sex. A linear mixed model was applied to estimate the effects of cassava inclusion. The findings indicated feed and nutrient intake, particularly crude protein intake and nitrogen retention, increased significantly (p<0.05), while crude protein digestibility showed no significant difference. Microbiological parameters, including total bacterial and fungal counts, also increased significantly (p<0.05), whereas methane production after 24 hours declined significantly (p<0.05). Although production parameters such as body weight, feed conversion, and milk yield were not significantly affected, a trend toward improvement was observed, except for feed conversion. Cassava root and foliage exhibited the highest digestibility and nitrogen retention compared to by-product (p<0.05). A restricted feeding system resulted in higher ammonia (NH3-N) concentrations, protozoa count, and proteolytic and cellulolytic microbial populations compared to ad libitum feeding and an extensive system (p<0.05). Murrah buffaloes showed greater feed intake, while male buffaloes demonstrated higher digestibility (p<0.05). In conclusion, dietary cassava, approximately 1.5% to 20.5% DM, potentially stimulates rumen fermentation, nutrient intake, digestibility, and microbiology but has only a modest effect on production parameters. High cassava inclusion may reduce feed acceptability, thereby decreasing feed efficiency.