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All Journal Pharmacology and Clinical Pharmacy Research
Tri U. Pratiwi
Department Of Anesthesiology And Reanimation, Faculty Of Medicine, Universitas Sriwijaya, Palembang, Indonesia
Medicine & Pharmacology

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Pharmacogenomic Considerations In Propofol: A Review Ziske Maritska; Tri U. Pratiwi; Muhammad J. Aldwin; Clinton F.M Sitanggang; Ferdy Rahadiyan
Pharmacology and Clinical Pharmacy Research Vol 8, No 1 (2023)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v8i1.38749

Abstract

Pharmacogenomics is one of the pivotal fields of science in the era of precision medicine. It helps provide an understanding of what causes the differences in terms of pharmacokinetics and pharmacodynamics of a particular drug in patients. Hence, this leads to better efficacy. This branch of medicine also applies to sedative drugs in the anesthesia field, one of which is propofol. Changes in propofol pharmacokinetics and pharmacodynamics properties might lead to toxicity and inadequate sedation. This review wishes to better understand how pharmacogenomics is applied in anesthesia, especially in propofol, one of its most commonly used medications.     
Co-Authors Clinton F.M Sitanggang Ferdy Rahadiyan Muhammad J. Aldwin Ziske Maritska