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All Journal Indonesian Journal of Urology Journal of Medicine and Health
Aaron T Sihombing, Aaron T
Department of Urology, Faculty of Medicine/Padjadjaran University, Hasan Sadikin Hospital, Bandung.
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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The Relationship between Body Mass Index (BMI) and Gleason Score of Indonesian Prostate Cancer Men in Hasan Sadikin General Hospital Abdurrahman, Fauzan; Suryanti, Sri; Sihombing, Aaron T
Journal of Medicine and Health Vol. 2 No. 2 (2018)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (485.419 KB) | DOI: 10.28932/jmh.v2i2.1022

Abstract

The risk of high grade PCa in Asia in relation to BMI had positive or negative effect. The objective of this study is to know the relationship between BMI and Gleason score in Indonesian PCa patients. A cross sectional study was conducted in Hasan Sadikin General Hospital. The data were secondary data taken from medical records of prostate adenocarcinoma patients in Hasan Sadikin General Hospital. Ordinal data were analyzed using Chi square and correlation using Spearman. All calculation was done using SPSS 24. There were 95 Indonesian PCa patients. 78 patients is in normal BMI range. Of those 41 patients (52.6%) is in high level of Gleason score. 17 patients is in high BMI range. High Gleason score was found in 11 patients (P = 0.362; rs = 0.094). Conclusion, there is no relation between BMI in Indonesian PCa and Gleason score.   Keywords : Prostate adenocarcinoma (PCa); BMI; Gleason score.
ANGIOTENSIN II TYPE-1 RECEPTOR (AT1R) DISTRIBUTION IN BPH, HIGH GRADE PIN AND ADENOCARCINOMA OF THE PROSTATE Septiadi, Isdianto; Sugandi, Suwandi; Noegroho, Bambang S; Tjahjodjati, Tjahjodjati; Safriadi, Ferry; Siregar, Safendra; Adriansjah, Ricky; Adi, Kuncoro; Sihombing, Aaron T; Pramod, Sawkar V; Nasution, Ramlan; Hernowo, Betthy S
Indonesian Journal of Urology Vol 17 No 2 (2010)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v17i2.348

Abstract

Objective: The aim of the study was to detect the differences in number and the distribution of angiotensin II type-1 receptor (AT1R) in BPH, high grade PIN, and adenocarcinoma of the prostate. Material & method: A prospective study was performed in RSHS, in collaboration with the Department of Anatomical Pathology. Prostate samples were taken by TUR of the prostate, and then divided into 5 groups. They were BPH, high grade PIN, adenocarcinoma of the prostate in 3 difference grades (well, moderate, and poorly differentiated). Kidney tissue for control. Immunohistochemical staining was done to determine the angiotensin II type-1 (AT1R) receptor distribution as primary antibody used was mouse monoclonal antibody AT1 (TONI-1): sc-57036, Santa Cruz Biotechnology Inc., CA. Results: Angiotensin II type-1 receptor was found in material of BPH, high grade PIN and adenocarcinoma of the prostate. The number and distribution of the receptors were not different. Conclusion: There are no significant differences in number and distribution of angiotensin II type-1 receptor on BPH, high grade PIN, and adenocarcinoma of the prostate.
Co-Authors Abdurrahman, Fauzan Bambang S Noegroho Betthy S Hernowo, Betthy S Ferry Safriadi Isdianto Septiadi, Isdianto Kuncoro Adi Muhammad Rivai Ricky Adriansjah Safendra Siregar Sawkar V Pramod, Sawkar V Sri Suryanti Suwandi Sugandi Tjahjodjati