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All Journal International Journal of Public Health Science (IJPHS) Indonesian Journal of Urology Eduvest - Journal of Universal Studies
Marta Hendry, Marta
Department Of Urology, Faculty Of Medicine/Airlangga University, Soetomo Hospital. Jl. Prof. Dr. Moestopo 6-8, Surabaya 60286
Aerospace Engineering Computer Science & IT Health Professions Medicine & Pharmacology Neuroscience Public Health Social Sciences

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INTRATESTICULAR INJECTION OF 20% HYPERTONIC SODIUM CHLORIDE AS A NOVEL CASTRATION METHOD: A PRECLINICAL STUDY Hendry, Marta; Hardjowijoto, Sunaryo; Purnomo, Basuki B; Joewarini, Endang; Meles, Dewa Ketut; P, Widodo J
Indonesian Journal of Urology Vol 17 No 1 (2010)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v17i1.339

Abstract

Objectives: To demonstrate that intratesticular injection of 20% hypertonic sodium chloride can result in permanent castration and to evaluate serum changes in sodium chloride levels. Materials and Methods: A total of 40 Wistar rats were divided into 4 groups, consisting of bilateral orchidectomy (n=10), control (n=10) and 2 groups receiving intratesticular injections of 20% sodium chloride (n=10 in each group). Serum testosterone was measured on day 0, day 1, day 15 and day 30. Serum sodium chloride was assessed before injection, at 1 hour and 24 hours after injection. All testicles were harvested for histological examination. One way ANOVA and student t-test were used for statistical analysis. Results: Serum testosterone decreased to castrate levels in the orchidectomy and injected groups with no significant difference (p>0,05). Significant rise in serum sodium chloride was found 1 hour post injection (p<0,05) but after 1 day it decreased significantly (p<0,05). There was no significant difference in histopathological findings between the 2 injected groups after day 15 and 30 (p>0,05). Conclusion: Twenty percent hypertonic chloride injection has the same permanent castration effect with bilateral orchidectomy in rats. The serum sodium chloride changes did not reach the lethal level for rats. Therefore this treatment has a promising potential as a novel and cost-effective castration method with the additional benefit of retaining both testes.
Prevalence of hypospadias patients with undescended testis Abrar Arbhiwa Tanguirsyaf Siregar; Shalita Dastamuar; Theodorus Theodorus; Marta Hendry
International Journal of Public Health Science (IJPHS) Vol 8, No 2: June 2019
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (305.24 KB) | DOI: 10.11591/ijphs.v8i2.19149

Abstract

Hypospadias is an anomaly of meatus urethra externus on ventral penis. It caused by incomplete fusion of urethral folds. The purpose of this study was to investigate the prevalence of hypospadias with undescended testis in the Department of Surgery Mohammad Hoesin Hospital in Palembang Indonesia. A prevalence study was done in the Medical Records Department of Mohammad Hoesin Hospital from July 2018 to February of 2019. 103 patients met study inclusion criteria. Univariate analysis of the patients’ data was conducted using IBM SPSS Statistics 25. The study found that hypospadias was most common in the age group of 1 to 5 years old (49.5%) and the most common type of hypospadias was severe hypospadias (68.9%). Furthermore, 7 out of 103 patients (6.8%) were hypospadias patients with undescended testis and the most common types of undescended testis among them were bilateral undescended testis and left undescended testis with 3 patients each (42,85%). Prevalence of hypospadias with undescended testis were 7 people (6,8%).
A MULTICENTER STUDY OF BENIGN PROSTATIC HYPERPLASIA PATIENTS UNDERGOING TRANSURETHRAL RESECTION OF THE PROSTATE IN INDONESIA: A DESCRIPTIVE ANALYSIS Daryanto, Besut; Penta Seputra, Kurnia; Satyagraha, Paksi; Nur Budaya, Taufiq; Kurniawan Dhani, Fauzan; Rasyidan Yulizar, Deddy; Hendry, Marta; Rhomdhon, Andrie; Ambeng, Yudi; Akhmad Adhi, Ryan
Indonesian Journal of Urology Vol 32 No 1 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i1.1018

Abstract

Objective: The study aims to provide a detailed understanding of the patient demographics and clinical features associated with TURP procedures in several tertiary hospital in Indonesia. Material & Methods: This study is a descriptive cross-sectional study conducted at four provinces in Indonesia. Patient data were collected from January 2021 to December 2023, including all patients diagnosed with BPH and who underwent TURP. The data were analyzed using the Statistical Package for Social Sciences (SPSS) version 28.0 (SPSS Inc., Chicago, Illinois, USA). Results: A total of 812 patients met the inclusion criteria for the study. The highest number of patients undergoing TURP (Transurethral Resection of Prostate) was at Saiful Anwar General Hospital, with 287 patients. The average prostate volume across all patients was 57.6±20.6 ml with an IPP (Intravesical Prostatic Protrusion) of 13.0±5.2 ml. Diabetes Mellitus was the most common comorbidity among the patients, affecting 271 patients (33.3%). Urinary retention was the most frequent reason for patients undergoing TURP, affecting 664 patients (81.7%), followed by bladder stones, which affected 58 patients (7.1%). Conclusion: Advanced age and a history of smoking are the primary clinical features observed in BPH patients undergoing TURP in Indonesia. Additionally, urinary retention has been identified as the main indication for TURP procedures in these patients. Keywords: TURP, BPH, IPP.
DARTOS FASCIA AS AN INTERPOSITIONAL LAYER IN HYPOSPADIAS URETHROPLASTY: A SYSTEMATIC REVIEW Hendry, Marta; Murti, Krisna; Daryanto, Besut; Liberty, Iche Andriyani
Eduvest - Journal of Universal Studies Vol. 5 No. 12 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i12.52502

Abstract

This systematic review evaluated the role of dartos fascia as an interpositional layer in primary hypospadias repair. Search was conducted in PubMed, EMBASE, Scopus, CENTRAL, and Web of Science (2019–2025) for studies in patients ≤18 years undergoing hypospadias repair. Primary outcomes were urethrocutaneous fistula (UCF), dehiscence, meatal/urethral stenosis, and reoperation; secondary outcomes were infection and cosmetic scores. Narrative synthesis was used. Results: Eleven studies met criteria, predominantly distal TIP. No randomized trial compared any second layer versus none; one cohort (n=425) showed similar UCF with periurethral/dartos coverage versus none (6.7% vs 7.3%). A randomized trial favored double- over single-layer dartos (3.3% vs 23.3%). Another trial found ventral preferable to dorsal dartos with fewer flap-related complications at similar UCF rates. Tunica vaginalis flap reduced UCF and improved cosmetics but is more invasive. Platelet-rich fibrin adjunct lowered UCF and infection in two studies. Spongioplasty produced comparable UCF but higher meatal stenosis, though selected robust spongiosum allowed zero fistulas. Conclusion: Dartos remains the workhorse; double-layer and ventral harvest optimize outcomes, while tunica vaginalis and PRF offer effective alternatives in selected cases. Further randomized trials are needed to clarify the necessity of a second layer.
Co-Authors Abrar Arbhiwa Tanguirsyaf Siregar Akhmad Adhi, Ryan Ambeng, Yudi Basuki B Purnomo, Basuki B Dastamuar, Shalita Endang Joewarini Iche Andriyani Liberty, Iche Andriyani Krisna Murti Kurniawan Dhani, Fauzan Meles, Dewa Ketut Nur Budaya, Taufiq Paksi Satyagraha Penta Seputra, Kurnia Rasyidan Yulizar, Deddy Rhomdhon, Andrie Sunaryo Hardjowijoto Theodorus Theodorus Widodo J P