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All Journal Indonesian Journal of Urology Jurnal Sosial dan Sains Surabaya Biomedical Journal
Ariyo Sakso Bintoro
Universitas Hang Tuah
Astronomy Dentistry Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Nursing Physics Public Health

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PENGARUH PEMBERIAN KONTRAS MEDIA NON IONIK LOW OSMOLAR INTRA VENA TERHADAP KADAR CYSTATIN–C SERUM PADA ORYCTALAGUS CUNICULUS Bintoro, Ariyo Sakso; Soetojo, Soetojo; Soebadi, Doddy M
Indonesian Journal of Urology Vol 15 No 2 (2008)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v15i2.354

Abstract

Objective: To measure effects of low osmolar non ionic contrast media on cystatin–C serum levels on different days after administration. Material and Method: Twenty-two oryctalagus cuniculus were divided into two groups of 11 subjects, each subject receiving intravenous injection of low osmolar non ionic contrast or a placebo solution (NaCl 0,9%). Cystatin-C serum levels of each subject were measured before injection, on days 1, 3, 7, and 10. Cystatin–C serum levels were determined with a sandwich ELISA method. Statistical analysis was performed with t–test. Results: Mean cystatin–C serum levels before injection was 0,00337 ± 0,00101 mg/L. Means from days 1, 3, 7, and 10 after injections were 0,00498 ± 0,00153 mg/L; 0,00565 ± 0,00247 mg/L; 0,00468 ± 0,00157, and 0,00339 ± 0,00188 mg/L respectively. Conclusion: Increase in serum cystatin–C levels on days 1, 3, and 7 was significant. On the 10th day no significant escalation was observed. Compared to the control group, there were significant differences in serum cystatin–C increase on days 1 and 3 in the intervention group, but no significant differences 7 and 10 days after injection.
Gut Microbiota On Erectile Dysfunction : a Systematic Review Dwiprawira, Revantoro Artha; Bintoro, Ariyo Sakso
Jurnal sosial dan sains Vol. 5 No. 6 (2025): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/jurnalsosains.v5i6.32252

Abstract

Erectile dysfunction (ED) has significant physical and psychological effects on both patients and their partners. Beyond disrupting sexual relationships and family dynamics, ED is often associated with comorbidities such as anxiety, depression, and other mental health disorders. A potential relationship is suggested by variations in our gut microbiota the composition between ED patients and healthy people. This study aims to evaluated relationship between gut microbiota and ED. Materials & Methods : A systematic review was conducted with PRISMA 2020 guidelines, with PICO framework to focus on individuals with ED. The intervention analyzed was gut microbiota compared to healthy controls, with the primary outcome being gut microbiota associated with ED. Search was performed across PubMed, Scopus, Web of Science, and Cochrane Library from 2020 to 2025 using keywords such as "gut microbiome," "gut microbiota," "intestinal microbiome," and "gut flora" combined with "erectile dysfunction." Inclusion and exclusion criteria were applied, and the risk of bias in studies was assessed using the Newcastle-Ottawa Quality Assessment Scale. Results : A total of 64 studies underwent screening, 7 were included in the final analysis. The results showed correlation between ED and changes in the gut microbiota. A higher risk of ED was associated with increased populations of Lachnospiraceae, Oscillibacter, Tyzzerella3, Senegalimassilia, and Actinomyces. On the other present, a lower risk of ED was related to Ruminococcaceae UCG013, Coprococcus 1, Lachnospiraceae FCS020, Prevotella, and Bifidobacterium. Moreover, ED patients had more species of Streptococcus, Subdoligranulum, Bacteroides, Fusobacterium, and Escherichia-Shigella genera compared to species Blautia, Roseburia, Ruminiclostridium 5, and Lactococcus. Conclusion : The role of gut microbiota in ED, with Lachnospiraceae, Oscillibacter, Tyzzerella3, and Senegalimassilia increasing risk, while Ruminococcaceae UCG013 is protective. However, further research is needed to understand microbial mechanisms and explore gut microbiota modulation as a potential therapeutic strategy.
KARAKTERISTIK PASIEN CHRONIC KIDNEY DISEASE YANG MENJALANI HEMODIALISIS DI RSKD DUREN SAWIT JAKARTA TIMUR PERIODE JULI-DESEMBER 2024 Rendy Putra Evans Ginting; Christina Rusli; Ariyo Sakso Bintoro; Nabil Bahasuan
Surabaya Biomedical Journal Vol. 5 No. 3 (2026): May
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/v5i3.195

Abstract

Chronic Kidney Disease (CKD) adalah kondisi di mana terjadi kerusakan ginjal selama minimal tiga bulan, ditandai oleh perubahan pada struktur atau fungsi ginjal. Diagnosis CKD ditegakkan berdasarkan adanya kelainan patologis atau penurunan laju filtrasi glomerulus (GFR). Pasien CKD yang memiliki GFR di bawah 15 mL/menit/1,73 m² memerlukan prosedur dialisis. Pada tahun 2020, sebanyak 61.786 warga Indonesia dengan CKD menjalani prosedur dialisis. Penelitian ini bertujuan untuk mengetahui karakteristik pasien CKD yang menjalani hemodialisis. Desain pada penelitian ini adalah deskriptif. Sampel penelitian ini terdiri dari seluruh pasien CKD yang menjalani hemodialisis, berdasarkan data yang tercatat di rekam medis RSKD Duren Sawit Jakarta Timur selama periode Juli hingga Desember 2024. Penelitian ini dilaksanakan pada periode Maret-Oktober 2025. Hasil penelitian menunjukan lebih dari setengah pasien CKD yang menjalani hemodialisis di RSKD Duren Sawit Jakarta Timur berada dalam kelompok usia 40-60 tahun (56%) dan mayoritas pasien laki-laki (57%). Faktor risiko yang paling banyak diderita pasien merupakan hipertensi (44%) lalu diabetes melitus dan paling sedikit mengalami asam urat (2%). Mayoritas pasien memiliki kadar kreatinin >1,5 mg/dl (96%). Status gizi pasien mayoritas termasuk kelompok tidak normal (57%). Hampir seluruh pasien (95%) memiliki kadar hemoglobin dibawah kadar normal, serta seluruh pasien menggunakan BPJS sebagai sumber biaya selama menjalani hemodialisi. Pasien CKD yang menjalani hemodialisis di RSKD Duren Sawit selama periode Juli hingga Desember 2024 mayoritas adalah kelompok usia 40-60 tahun, mayoritas pasien laki-laki, dengan faktor risiko hipertensi, memiliki kadar kreatinin, hemoglobin, dan status gizi yang tidak dalam batas normal, serta seluruh pasien menggunakan BPJS sebagai sumber biaya hemodialisis.
Co-Authors Christina Rusli Doddy M Soebadi Dwiprawira, Revantoro Artha Nabil Bahasuan Rendy Putra Evans Ginting Soetojo Soetojo