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Ahmad Syukur Hasibuan
Institut Kesehatan Medistra
Health Professions Nursing Public Health

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SOSIALIASI SKRINING FITOKIMIA EKSTRAK ETANOL UMBI BAWANG MERAH (Allium cepa L.) Ahmad Syukur Hasibuan; Vicky Edrianto
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 1 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (443.116 KB) | DOI: 10.35451/jpk.v1i1.732

Abstract

Bawang merah (Allium cepa L) banyak mengandung senyawa aktif yang memiliki efek farmakologi. Etanol adalah pelarut yang mempunyai universal serta memiliki sifat netral, absorbsi baik, tidak beracun dan stabil sehingga dapat digunakan untuk ekstraksi umbi bawang merah. Skrining fitokimia dilakukan untuk mengetahui golongan senyawa yang terkandung dalam ekstrak umbi bawang merah. Penelitian ini dilakukan ekstraksi menggunakan metode maserasi selama 5 hari dan dilanjutkan dengan remaserasi selama 2 hari. Kemudian ekstrak yang didapat dilakukan skrining fitokimia. Hasil skrining fitokimia umbi bawang merah menggunakan pelarut etanol menunjukkan adanya kandungan senyawa flavonoid, tanin, saponin, alkaloid dan steroid/terpenoid. Sosialiasasi hasil skrining ekstrak etanol umbi bawang merah tersebut dilakukan terhadap mahasiswa pada saat pengajaran di kelas menggunakan aplikasi zoom.
SOSIALISASI UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KEDONDONG (Spondias dulcis Frost) TERHADAP TIKUS JANTAN YANG DIINDUKSI KARAGENAN Ahmad Syukur Hasibuan
JURNAL PENGMAS KESTRA (JPK) Vol 1 No 2 (2021): Jurnal Pengmas Kestra (JPK)
Publisher : Lembaga Penelitian dan Pengabdian Kepada Masyarakat (LP2M) Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (560.898 KB) | DOI: 10.35451/jpk.v1i2.913

Abstract

In the treatment of inflammation, there are several chemical drugs, namely steroidal and non-steroidal anti-inflammatory drugs, but because they have many side effects, anti-inflammatory drugs are developed from natural ingredients, especially plants. Plants that are scientifically proven to have anti-inflammatory properties, one of which is kedondong leaves because kedondong leaves contain flavonoid secondary metabolites as anti-inflammatory compounds. The method used in this study was paw edema, namely by induction of carrageenan 0.1 ml as an irritant on the soles of the rat's feet for 360 minutes with the parameter observed was the inhibition of edema in the feet of rats using a plethismometer. This study was an experimental study that was divided into 5 groups, namely the control group. positive (Diclofenac Sodium 9 mg/kgBW), negative control (Na-Cmc 0.55), and three doses tested, namely 100 mg/kgBW, 300 mg/kgBW and 500 mg/kgBW. The results of this study showed a significant difference (P> 0.05) with the conclusion that the three doses tested, namely 100 mg/kgBW, 300 mg/kgBW and 500 mg/kgBW had an anti-inflammatory effect where the more effective dose was 300 mg/kg kgBB.
Co-Authors Vicky Edrianto