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All Journal Jurnal Ilmiah Farmasi INDRA: Jurnal Pengabdian kepada Masyarakat
Mi'rajunnisa
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Health Professions Medicine & Pharmacology

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Edukasi penyalahgunaan obat-obatan di kalangan remaja pada siswa siswi SMAN 1 Beruntung Baru Yulianita Pratiwi Indah Lestari; Hendera; Mi'rajunnisa; Asyfa Putri Ramadhani; Cindy Cenora; Hilmalia; Malinda Apriliani; Muhammad Samawi
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 1 (2023): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/indra.v4i1.186

Abstract

Teenagers today are getting used to the use of various illegal drugs, which aim to get temporary pleasure or as an escape from their problems. The use of various types of drugs in high doses causes various negative impacts for adolescents such as damage to the central nervous system, seizure disorders due to respiratory and heart muscle spasms, dehydration, heart attacks, and even a worse effect that cause death. In the residential environment, formal and non-formal figures are expected to participate actively in fostering and providing guidance and direction to young people. This outreach activity was carried out among teenagers so that they know and were aware of the consequences of drug abuse. This activity was expected to increase adolescent knowledge about illegal drugs. The implementation of counseling as one of the community service programs for the Faculty of Pharmacy Lecturers together with the D3 Pharmacy Students of the University of Muhammadiyah Banjarmasin at SMAN 1 Beruntung Baru entitled "Education of Drug Abuse among Teenagers in SMAN 1 Beruntung Baru" has been carried out well and received a positive response from the students.
The analysis of hydroquinone levels in the product of whitening hand and body lotion in online shops, using the UV-Vis spectrophotometry method Mellynia, Sri Agfa; Lestari, Yulianita Pratiwi Indah; Mi'rajunnisa
Jurnal Ilmiah Farmasi Vol. 21 No. 2 (2025): Jurnal Ilmiah Farmasi
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jif.vol21.iss2.art6

Abstract

Background: Hydroquinone serves as a skin-lightening agent by suppressing melanin production. However, its usage in cosmetic formulations has been prohibited under the Indonesian Food and Drug Authority regulations, as stated in Regulation Number 18 of 2015. Despite this restriction, numerous studies show that various whitening hand and body lotion products commonly contain hydroquinone.Objective: This study aimed to conduct a qualitative and quantitative analysis of hydroquinone in body-whitening hand and body lotion products available through online retail platforms.Method: The methodology employed in this study involved the use of Thin Layer Chromatography (TLC) for qualitative analysis, complemented by UV-Vis spectrophotometry, which had undergone prior validation to serve as a quantitative analytical tool.Results: The qualitative analysis conducted via Thin Layer Chromatography (TLC) identified six positive samples containing hydroquinone, characterized by an Rf value of 0.75. According to the validation results, the method demonstrated a linearity value with a correlation coefficient (r) of 0.9976, a limit of detection (LOD) of 0.3862 g/mL, and a limit of quantification (LOQ) of 1.2872 g/mL. An RSD value of 1.912% showed precision, while accuracy was confirmed through a recovery rate of 96.77%. The validation outcomes suggested that this approach is robust for analyzing hydroquinone in body-whitening hand and body lotion products. The UV-Vis spectrophotometry result showed that samples 1 through 6 had hydroquinone in them at levels of 0.0418, 0.0448, 0.0361, 0.0283, 0.0365, and 0.3193%, respectively.Conclusion: The research conducted revealed that the qualitative analysis using Thin-Layer Chromatography (TLC) yielded six positive samples, indicating the presence of hydroquinone. Furthermore, the quantitative analysis indicated that whitening hand and body lotion products available in online shops contained hydroquinone at concentrations ranging from 0.0283 to 0.3193 g/mL. This finding underscores the continued prevalence of prohibited chemicals in certain cosmetic products.
Co-Authors Asyfa Putri Ramadhani Cindy Cenora Hendera Hendera Hilmalia Malinda Apriliani Mellynia, Sri Agfa Muhammad Samawi Yulianita Pratiwi Indah Lestari