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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran Cermin Dunia Kedokteran
Laura Agnestasia Djunaedi
Fakultas Kedokteran Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Funduskopi untuk Prognosis Preeklampsia Ferdy Iskandar; Laura Agnestasia Djunaedi; Angela Shinta Dewi Amita; Sigit Pradono Diptoadi
Cermin Dunia Kedokteran Vol. 45 No. 3 (2018): Muskuloskeletal
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i3.816

Abstract

Hipertensi dalam kehamilan (HDK) merupakan masalah kesehatan yang perlu mendapat perhatian karena mengakibatkan lebih dari 25% kematian ibu di Indonesia pada tahun 2013. Pada preeklampsia – yang merupakan salah satu HDK – terjadi disfungsi endotel berbagai organ ibu hamil, termasuk organ mata. Konsekuensi tersering adalah vasospasme umum disertai kebocoran plasma yang menyebabkan iskemi retina hingga kerusakan visus permanen. Derajat kelainan retina ibu hamil berdasarkan klasifikasi Keith-Wagener-Barker berbanding lurus dengan angka kematian serta angka kecacatan penglihatan. Funduskopi sebagai salah satu sarana pelengkap dapat menjadi sarana objektif memperkirakan prognosis ibu hamil dan status janin.   Hypertension in pregnancy is a health problem since it causes more than 25% of maternal deaths in Indonesia in 2013. In preeclampsia – type of hypertension in pregnancy – there are endothelial dysfunctions in various organs, including eyes. The most common consequences are general vasospasms with plasma leakage causing retinal ischemia leading to permanent damage. There is a linear correlation between KeithWagener-Barker classification and probability of death and blindness. Funduscopy can be used as a supplementary examination to help decide the best management and may be an objective tool for estimating prognosis of mother as well as fetal status.  
Funduskopi untuk Prognosis Preeklampsia Ferdy Iskandar; Laura Agnestasia Djunaedi; Angela Shinta Dewi Amita; Sigit Pradono Diptoadi
Cermin Dunia Kedokteran Vol 45 No 3 (2018): Muskuloskeletal
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v45i3.816

Abstract

Hipertensi dalam kehamilan (HDK) merupakan masalah kesehatan yang perlu mendapat perhatian karena mengakibatkan lebih dari 25% kematian ibu di Indonesia pada tahun 2013. Pada preeklampsia – yang merupakan salah satu HDK – terjadi disfungsi endotel berbagai organ ibu hamil, termasuk organ mata. Konsekuensi tersering adalah vasospasme umum disertai kebocoran plasma yang menyebabkan iskemi retina hingga kerusakan visus permanen. Derajat kelainan retina ibu hamil berdasarkan klasifikasi Keith-Wagener-Barker berbanding lurus dengan angka kematian serta angka kecacatan penglihatan. Funduskopi sebagai salah satu sarana pelengkap dapat menjadi sarana objektif memperkirakan prognosis ibu hamil dan status janin.   Hypertension in pregnancy is a health problem since it causes more than 25% of maternal deaths in Indonesia in 2013. In preeclampsia – type of hypertension in pregnancy – there are endothelial dysfunctions in various organs, including eyes. The most common consequences are general vasospasms with plasma leakage causing retinal ischemia leading to permanent damage. There is a linear correlation between KeithWagener-Barker classification and probability of death and blindness. Funduscopy can be used as a supplementary examination to help decide the best management and may be an objective tool for estimating prognosis of mother as well as fetal status.  
Selenium sebagai Terapi Oftalmopati Graves Derajat Ringan Laura Agnestasia Djunaedi; Ferdy Iskandar; Cisca Kuswidyati
Majalah Kedokteran Indonesia Vol 69 No 8 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.8-2019-190

Abstract

Graves ophthalmopathy (GO) is the most common extrathyroid manifestation of Graves’ disease. More than 50% of Graves’ patients will experience it, even 10% of them will suffer severe GO. The mechanism of GO is associated with complex autoimmune reaction and suspected to be associated with an imbalance levels of antioxidants and oxidants in the body. Smoking and poor control of Graves’ disease also trigger the progression of ophthalmopathy.Selenium is one of the most abundant antioxidant components in the thyroid gland. Selenium can help overcome mild GO by correcting the imbalance between oxidant and antioxidant levels in the body. Nevertheless, selenium cannot be given carelessly because improper dosing can lead to the several types of cancer as well as type 2 diabetes mellitus.
Co-Authors Angela Shinta Dewi Amita Cisca Kuswidyati Ferdy Iskandar Ferdy Iskandar Sigit Pradono Diptoadi