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All Journal Open Access Indonesian Journal of Medical Reviews
Heni Setyoningsih
Bachelor of Pharmacy Study Program, ITEKES Cendekia Utama Kudus, Kudus, Indonesia
Health Professions Medicine & Pharmacology

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Antioxidant Activity of Leucaena leucocephala Lmk.de Wit. N-Hexane Fraction Ricka Islamiyati; Yanulia Handayani; Kadar Ismah; Gendis Purno Yudanti; Heni Setyoningsih; Sri Fitrianingsih
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 1 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i1.286

Abstract

Antioxidants are chemical compounds that can neutralize free radical agents. These compounds work by donating electrons to achieve a stable form, thereby inhibiting the oxidative mechanisms that cause degenerative disease. Lamtoro seeds contain many active compounds that can be used as a source of natural antioxidants and antibacterials. This study aimed to determine the antioxidant effect of the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk. de Wit.). This study is an in vitro experimental study. The object of study was the n-hexane fraction of lamtoro seeds, where antioxidant activity was examined using the DPPH method. Analysis was performed using a UV-Vis spectrophotometer. The n-hexane fraction contained a total flavonoid content of 9.224% and had antioxidant activity with an lC50 value of 67.94 ppm. In conclusion, the n-hexane fraction of lamtoro seeds (Leucaena leucocephala Lmk.de Wit.) has strong antioxidant activity.
Co-Authors Gendis Purno Yudanti Kadar Ismah Ricka Islamiyati Sri Fitrianingsih Yanulia Handayani