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All Journal Jurnal Zarah Journal of Pharmaceutical and Sciences.
Mahmudi , Mahmudi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Analisis Pemahaman Konsep Siswa Kelas XI IPA SMAN 1 Malang Pada Topik Bentuk Molekul Sabekti, Ardi Widhia; Widarti, Hayuni Retno; , Mahmudi
Jurnal Zarah Vol 2 No 1 (2014): Jurnal Zarah
Publisher : Program Studi Pendidikan Kimia, Fakultas Keguruan dan Ilmu Pendidikan Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.088 KB)

Abstract

Analisis Pemahaman Konsep Siswa Kelas XI IPA SMAN 1 Malang  pada Topik Bentuk Molekul. The purpose of research is to identify: (1) student’s understanding level about molecular shape, (2) student’s misconception about molecular shape, and (3) student’s ability to fulfill the problems in Indonesian language and English language about molecular shape. Research uses quantitative descriptive design. Populations are 11th Grade Science Students of SMAN 1 Malang in 2010/2011 academic year that consist of 6 classes. Samples are students of 11th Grade Science 1, 3, and 4. Sampling technique is simple random sampling, which takes the sample member randomly without concern in population’s strata. Instrument in research is 20 problems objective test; consist of 10 problems in Indonesian language and 10 problems in English language. Instrument’s reliability is 0.73 and the validity is 98.3%. Every problem has 5 alternative answers that are supported by reason of answer and interview result. Research result indicates that (1) Student’s understanding level about molecular shape is medium (54.5%). If regarded from aspects those are measured, student’s understanding about bond angle is medium (53.7%); students’ understanding about stability of molecule based on lone pair placement is medium (54.9%); prediction of molecular shape is high (60.1%); students’ understanding about the polarity of molecule is medium (40.7%); hybrid orbital is high (70.6%); and students’ understanding about hybridization process is medium (46.7%). (2) The student’s misconceptions are: (a) fewer amount of bonding pair, the value of bond angle is bigger (3.9%); (b) double bond donate two bonding pair (2.9%); (c) lone pair is not has effect in molecular shape prediction (25.5%). (3) Student’s ability to fulfill the problems in Indonesian language (55.78%) is equal with student’s ability to fulfill the problems in English language (56.07%).
Skrining fitokimia dan aktivitas antioksidan ekstrak etanol daging buah pala (Myristica fragrans) kawasan Aceh Selatan, Indonesia. Azhari , Saiful; Kurniaty , Rina; Yusuf, Muhammad; Zulyani , Riza; Mahmudi , Mahmudi; Rani, Wahyu Mustika; Farida , Mutia
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.421

Abstract

The nutmeg fruit (Myristica fragrans) shows the presence of secondary metabolite compounds and has antioxidant activity. The nutmeg examined in this study is the flesh of the fruit and dried for seven days to obtain simplisia. The extraction process is by maceration method using 96% ethanol solvent. Based on the results of phytochemical screening of ethanol extracts of nutmeg flesh showed the presence of secondary metabolite compounds, which are groups of alkaloids, steroids, saponins and flavonoids. The results of antioxidant activity of ethanol extract of nutmeg flesh have an IC50 value of 22.88 ppm. In this study using vitamin C as a positive control for comparison with the IC50 value obtained is 3.82 ppm. The more secondary metabolite compounds in an extract, the higher the antioxidant activity.
Vegetables, Heavy metals, FAAS, Kajian Cemaran Logam Berat Timbal (Pb), Kadmium (Cd), Dan Merkuri (Hg) Pada Sayuran Di Daerah Pertambangan Aceh Jaya Secara Spektrofotometri Serapan Atom. Kurniaty , Rina; Adiyana, T.M. Dayan; Yusuf , Muhammad; Mahmudi , Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.448

Abstract

Heavy metal contamination in vegetables poses a threat to humans, especially at predetermined thresholds. In this study, Pb, Cd, and Hg metals were analyzed using Flame - Atomic Absorption Spectrometry (F-AAS) and Vapor Generation Accesory - Atomic Absorption Spectrometry (VGA-AAS) methods at mining areas in Krueng Sabee Sub-District, Aceh Jaya District, Aceh Province. Method validation was conducted to obtain accurate heavy metal analysis results on the samples. The results showed that the highest Pb metal contamination was found in cassava leaf I sample with levels of 2.44 ± 1.33 mg/Kg and the lowest was found in spinach III sample with levels of 0.15 ± 0.07 mg/Kg. The high Pb content was also found in kale I and spinach I samples obtained in areas close to the mining area with levels of 1.07 ± 0.59 mg/Kg and 0.93 ± 0.50 mg/Kg, respectively. The highest Cd metal contamination content was found in kale II samples with levels of 0.11 ± 0.01 mg/Kg and the lowest Cd metal contamination with levels of 0.02 ± 0.01 mg/Kg was found in cassava leaf II samples. The highest Hg metal content of 0.58 ± 0.12 mg/Kg was found in cassava leaf I sample and the lowest level was 0.04 ± 0.02 mg/Kg owned by spinach III sample. Contamination of Hg metal in all vegetable samples showed levels that were above the established SNI 7387 (2009) quality standard of 0.03 mg/Kg. The quality standards for Pb and Cd metal contamination are 0.5 mg/Kg and 0.2 mg/Kg, respectively.  This study shows the need for government monitoring of heavy metal contamination in agricultural areas near mining activities to ensure safe food consumption.
Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Daun Ciplukan (Physalis angulata L) Dikawasan Manifestasi Geothermal Seulawah Agam Farida , Mutia; Azhari , Saiful; Darsa , Dimas Dwi; Mahmudi , Mahmudi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.826

Abstract

Ciplukan leaves (Physalis angulata L.) from the Seulawah Agam geothermal manifestation area exhibit strong potential as a natural antioxidant source. This study investigates the phytochemical content and antioxidant activity of ethanol extract from ciplukan leaves using UV-Vis spectrophotometry. The research begins with sample collection and plant determination, followed by phytochemical screening and antioxidant activity testing using the DPPH method. Phytochemical screening results reveal the presence of alkaloids, flavonoids, tannins, saponins, and steroids. Antioxidant activity testing using the DPPH method yields an IC50 value of 14.99 μg/mL, significantly lower than the positive control, ascorbic acid (19.40 μg/mL), indicating strong antioxidant activity. At the highest tested concentration (50 μg/mL), the extract exhibits an inhibition percentage of 81.84%, while at the lowest concentration (10 μg/mL), it shows an inhibition of 41.41%. These findings confirm that the ethanol extract of ciplukan leaves from the geothermal area possesses high antioxidant content and has great potential for applications in the development of natural-based pharmaceutical and nutraceutical products.
Co-Authors Adiyana, T.M. Dayan Ardi Widhia Sabekti Azhari , Saiful Darsa , Dimas Dwi Farida , Mutia Hayuni Retno Widarti Kurniaty , Rina Muhammad Yusuf Rani, Wahyu Mustika Yusuf , Muhammad Zulyani , Riza