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METASTASIS AND LOCAL INVASION PATTERN OF BLADDER CANCER IN HASAN SADIKIN HOSPITAL Mustafa, Akhmad; Safriadi, Ferry
Indonesian Journal of Urology Vol 25 No 2 (2018)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v25i2.428

Abstract

Objective: The aim of this study is to provide database about local invasion and metastasis pattern, as well as the disease characteristics of bladder cancer in Hasan Sadikin Hospital, Bandung. Material & Methods: Between January 2011 and December 2016 there were 321 cases of bladder cancer recorded in our hospital. Of all cases, 106 patients included in this study, with evident of local invasion or distant metastasis either radiologically (contrast abdominal pelvic CT scan) or pathologically. Results: The study group consist of 106 patients (86 men [81.7%], 20 women [28.3%]); with mean age of 56.78 ± 13.19 (4-76) years old. Histopathology findings of transitional cell carcinoma (TCC) consist of 82 (77.3%) patients and the atypical histology features group of 24 (22.7%) patients. Local invasion was found in 99 patients of 321 (30.8%), with the most common organ invasion to the prostate in male (n=38 [35.8%]). Lymph node metastasis were found in 47 patients (44.3%), with the most common nodal metastasis to obturator lymph nodes (n=21 [19.8%]). Distant metastasis was found in 24 patients (22.6%) with the most common site for distant metastasis was the liver (n=12 [11.3%]). In TCC group, 12 patients (63.1%) had a distant organ metastasis with nodal metastasis, whereas in atypical group, majority of the patients with distant organ metastasis (n=5 [83.3%]) had no lymph node involvement. Moreover, in transitional cell group, not all patient (n=17 [73.1%]) had local invasion of the tumor, while all patients with distant organ metastasis in atypical group (n=6 [100%]) had abdominal or pelvic wall invasion (cT4b). Conclusion: TCC is the most common pathology findings and with Prostate is the most common site for local tumor invasion. Obturator lymph nodes is the most common nodal metastasis and liver is the most common site for distant metastasis in bladder cancer. 
TEN YEARS EXPERIENCE IN MANAGEMENT OF BLADDER TRAUMA AT TERTIARY HOSPITAL IN WEST JAVA INDONESIA Indra Firdaus, Gugum; Wijayanti, Zola; Mustafa, Akhmad; Adi, Kuncoro
Indonesian Journal of Urology Vol 31 No 1 (2024)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v31i1.834

Abstract

Objective: The aim of this study is to provide the characteristics, management, and outcome of bladder trauma at the center of trauma referral hospital in West Java, Indonesia. Material & Methods: This is a retrospective and descriptive study. The data of bladder trauma were collected from the medical records from January 2010 to December 2019. The data were presented using descriptive statistics in frequency and percentage. Results: Over a ten-year period, there were 1,174 cases of urogenital trauma, with 170 cases (14.48%) involving bladder injuries. The majority of the was 21-30 years old and were men (55.88%). The most common cause was blunt abdominal trauma (68.82%), which was caused by traffic accidents (91.45%). With 42.24% pelvic fracture as the most common associated injury. The most common type of bladder injury (45.88%) was bladder contusion. Iatrogenic trauma was the second leading causes (29.42%) with obstetrics and gynecology operations accounted for 84% of iatrogenic bladder trauma cases. The majority of bladder injuries were identified using a computed tomography (CT) scan. In 59.41% of cases, surgical intervention was required. The mortality rate was 2.94% during post-operative treatment due to coexisting or associated multiple injuries. Conclusion: We discovered that bladder trauma most commonly affects males of reproductive age with blunt abdominal trauma as the most common etiology and pelvic fractures as the most common associated injury. Surgical intervention often was required. Keywords: Bladder injury, blunt abdominal trauma, iatrogenic bladder injury.
SECONDARY BLADDER CARCINOMA METASTASIS FROM OTHER ORGAN: A LITERATURE REVIEW Wahyudi, Yuvi; Mustafa, Akhmad
Indonesian Journal of Urology Vol 32 No 2 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i2.945

Abstract

Objective: This review article discusses the importance of considering metastasis malignancy in the differential diagnosis of high-grade urothelial lesions. Material & Methods: The review presents a summary of metastasis of bladder carcinoma from various organs. The most common sources of secondary bladder tumors are stomach, breast, colon cancer, and melanoma. The article highlights the need for careful evaluation and further workup in patients being treated for metastatic cancer who present with hematuria and symptomatic anemia. Results: Diagnosis of secondary bladder carcinoma involves imaging, cystoscopy, and transurethral resection. Biopsies should be collected from patients with suspected urothelial bladder metastasis from other cancer origins or those with suggestive symptoms. The article emphasizes the importance of differentiating metastatic adenocarcinoma of the lung from primary bladder adenocarcinoma, especially when bladder examination does not correlate with imaging results. It also discusses the increased risk of secondary bladder carcinoma in rectal cancer survivors who have undergone radiation therapy. Conclusion: In conclusion, secondary bladder carcinoma metastasis from other organs presents a diagnostic dilemma and requires comprehensive evaluations. Healthcare professionals should consider metastasis malignancy in the differential diagnosis of high-grade urothelial lesions, especially in the absence of readily available clinical history of primary cancer. Keywords: Bladder cancer, secondary tumors, metastasis, differential diagnosis, primary cancer.
KARAKTERISTIK OSEANOGRAFI KIMIA SELAT TIWORO UTARA SEBAGAI DAYA DUKUNG LINGKUNGAN DALAM PENENTUAN LOKASI BUDIDAYA RUMPUT LAUT Eucheuma cottonii Pariakan, Arman; Mustafa, Akhmad; Indrayani, Miss
JFMR (Journal of Fisheries and Marine Research) Vol. 3 No. 3 (2019): JFMR
Publisher : Faculty of Fisheries and Marine Science, Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jfmr.2019.003.03.15

Abstract

Rumput laut Eucheuma cottonii merupakan produk baku yang memiliki peran dalam meningkatkan kesejahteraan pada daerah-daerah berkembang di masa depan, khususnya wilayah yang masuk kawasan perairan Selat Tiworo utara yakni klaster tinanggea. Untuk mendapatkan hasil produksi rumput laut E. cottonii yang optimal di lokasi pembudidayaan, maka perlu diketahui kekuatan daya dukung kimia perairannya. Penelitian ini bertujuan untuk mengetahui karakteristik oseanografi kimia terhadap pertumbuhan rumput laut Eucheuma cottonii di wilayah perairan Selat Tiworo utara klaster tinanggea. Penelitian ini dilakukan dengan metode purposive sampling, yang menjadi titik-titik lokasi pengukuran dan pengambilan peubah air. Hasil penelitian, menunjukkan bahwa karakteristik oseanografi kimia wilayah perairan Kecamatan Tinanggea dan Kecamatan Palangga Selatan sesuai untuk dilakukan kegiatan budidaya rumput laut E. cottonii.  Eucheuma cottonii Seaweed is a raw product that has a role in improving the welfare of the developing regions in the future, particularly the part that entered the area Tiworo Strait north as cluster Tinanggea. To get the production of E. cottonii seaweed optimal at the cultivation site, it is necessary to know the strength of the chemical carrying capacity of the waters. This study aims to determine the chemical oceanographic characteristics of the growth of Eucheuma cottonii seaweed in the Tiworo Strait waters north of the Tinanggea cluster. This research was done with a purposive sampling method, which became the location point for measuring and taking water variables. The results of the study showed that the chemical oceanographic characteristics of the waters area of Tinanggea District and Palangga Selatan District were suitable for conducting seaweed farming activities E. cottonii.
KONSENTRASI DAN STATUS MUTU LOGAM BERAT DALAM AIR DAN SEDIMEN DI KAWASAN PESISIR KABUPATEN KEPULAUAN SANGIHE Mustafa, Akhmad; Kamariah; Radiart, I Nyoman; Asaf, Ruzkiah
Jurnal Ilmu dan Teknologi Kelautan Tropis Vol. 13 No. 1 (2021): Jurnal Ilmu dan Teknologi Kelautan Tropis
Publisher : Department of Marine Science and Technology, Faculty of Fisheries and Marine Science, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jitkt.v13i1.35290

Abstract

Eksplorasi mineral logam tertentu dikhawatirkan dapat menyebabkan adanya limbah tambang berupa logam berat yang mencemari air dan sedimen di kawasan pesisir Kabupaten Kepulauan Sangihe, Provinsi Sulawesi Utara. Penelitian ini bertujuan untuk mengetahui konsentrasi dan status mutu logam berat dalam air dan sedimen sehubungan dengan potensi pencemaran yang mungkin terjadi dalam hubungannya dengan pengembangan marikultur. Penelitian dilaksanakan di kawasan pesisir Teluk Talengan, Manalu, dan Dagho dan sekitarnya dengan mengambil sampel air dan sedimen dan selanjutnya dianalisis di laboratorium untuk logam berat Cu, Fe, Hg, Pb, dan Zn. Statistik deskriptif digunakan untuk menganalisis data yang ada dan selanjutnya metode Storet (Storage and Retrieval) digunakan untuk menentukan status mutu air dan sedimen dari logam berat untuk biota laut. Hasil penelitian menunjukkan bahwa dari lima logam berat yang dianalisis dalam air dan sedimen, dijumpai satu di antaranya Hg yang tidak terdeteksi di kawasan pesisir Kabupaten Kepulauan Sangihe. Hasil penentuan status mutu air dan sedimen menunjukkan bahwa air di kawasan pesisir Kabupaten Kepulauan Sangihe tergolong tercemar berat dari logam berat Cu dan Pb untuk biota laut, sedangkan sedimennya tergolong memenuhi baku mutu logam berat untuk biota laut. Konsentrasi logam berat Cu dan Pb dalam air telah melampaui baku mutu logam berat untuk biota laut.