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Dian Anggraeny
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Journal : Acta Medical and Health Sciences (AMHS)

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Noise induced hearing loss among furniture factory workers PT Chitose Cimahi Yanti Nurrokhmawati; Desire M Nataliningrum; Dian Anggraeny
ACTA Medical Health Sciences Vol. 1 No. 1 (2022): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Noise Induced Hearing Loss (NIHL) merupakan masalah kesehatan yang cukup umum terjadi pada pekerja pabrik, termasuk di industri manufaktur furnitur. Paparan kebisingan yang melebihi ambang batas intensitas dalam waktu yang lama dapat menyebabkan gangguan pendengaran, baik bersifat sementara maupun permanen. Jika tidak ditangani dengan serius, kondisi ini dapat berdampak pada gangguan pendengaran maupun gangguan non-pendengaran. Tujuan dari penelitian ini adalah untuk mengetahui prevalensi gangguan pendengaran akibat kebisingan, karakteristik pekerja, lama kerja, kebiasaan penggunaan alat pelindung telinga (APD), serta gejala auditorik dan non-auditorik pada pekerja di PT Chitose, Cimahi, Jawa Barat. Subjek dalam penelitian ini adalah sebanyak 66 pekerja yang terdiri dari 62 laki-laki dan 4 perempuan, dipilih dengan metode total sampling. Penelitian dilakukan dengan metode deskriptif potong lintang (cross-sectional). Anamnesis dilakukan melalui pengisian kuesioner, pemeriksaan fisik telinga, dan pemeriksaan audiometri nada murni (pure tone audiometry). Hasil penelitian menunjukkan bahwa prevalensi NIHL ditemukan pada 37 orang (56%). Dari pasien dengan NIHL tersebut, rata-rata usia adalah 37,8 tahun, dengan mayoritas berjenis kelamin laki-laki (95%). Sebagian besar berasal dari bagian produksi (73%), dengan rata-rata lama kerja 16,6 tahun. Sebanyak 54% pekerja tidak pernah menggunakan APD. Gejala auditorik yang paling sering dirasakan adalah tinnitus (54%), sedangkan gejala non-auditorik yang paling sering dilaporkan adalah kesulitan tidur (19%). Kesimpulan: Prevalensi NIHL pada pekerja PT Chitose Cimahi tergolong tinggi. Hal ini disebabkan oleh paparan kebisingan dan dipengaruhi oleh berbagai faktor risiko. Oleh karena itu, diperlukan program pencegahan dari pihak perusahaan serta rehabilitasi bagi pekerja yang terdampak. Gangguan pendengaran yang ditemukan pada pekerja pabrik furnitur PT Chitose Cimahi merupakan gangguan pendengaran yang disebabkan oleh kebisingan. DOI : 10.35990/amhs.v1n1.p10-18 REFERENCES Sliwinska-Kowalska, M., & Davis, A. (2012). Noise-induced hearing loss. Noise & Health, 14, 274–280. Mazlan, N., Yahya, K., & Haron, Z. (2018). Characteristic of Noise-induced Hearing Loss among Workers in Construction Industries. E3S Web of Conferences, 34, 02025. Robinson, T., Whittaker, J., Acharya, A., Singh, D., & Smith, M. (2015). Prevalence of noise-induced hearing loss among woodworkers in Nepal: a pilot study. International Journal of Occupational and Environmental Health, 21(1), 14–22. Dement, J., Ringen, K., Welch, L., Bingham, E., & Quinn, P. (2018). Hearing loss among older construction workers: Updated analyses. American Journal of Industrial Medicine, 61(4), 326–335. Nelson, D., Nelson, R., & Barientos, M.C. (2005). The global burden of occupational noise-induced hearing loss. 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The Effects of Noise on Man (2nd ed., Ch. 2). London: Academic Press. Soetirto, I., & Bashiruddin, J. (2001). Gangguan pendengaran akibat bising. Disampaikan pada Simposium Penyakit THT Akibat Hubungan Kerja & Cacat Akibat Kecelakaan Kerja, Jakarta, 2 Juni. Lintong, F. (2009). Gangguan Pendengaran Akibat Bising. Jurnal Biomedik, 1(2), 81–86. Kandou, L.F., & Mulyono. (2013). Hubungan karakteristik dengan peningkatan ambang pendengaran penerbang. The Indonesian Journal of Occupational Safety and Health, 2(1), 1–9. Suryani, S., Mulyadi, A., & Afandi, D. (2015). Analisis Gangguan Pendengaran Tipe Sensorineural pada Pekerja akibat Kebisingan di Industri Mebel Kayu di Kota Pekanbaru. Jurnal Ilmu Lingkungan, 9(1), 1–11. Wald, P.H., & Stave, G.M. (2012). Physical and Biological Hazards of the Workplace (2nd ed., pp. 279–290). John Wiley & Sons, New York. Fatimah, S. (2008). Pengaruh Kebisingan terhadap Noise-Induced Hearing Loss (NIHL) Karyawan di PT. SCTI Jakarta Timur Tahun 2008. FKM UI. 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Effect of antioxidants on kidney damage repair in - diabetes-induced animal: a literature study Astri Pradini; Dian Anggraeny; Tatang Bisri; Diana Akmalia
ACTA Medical Health Sciences Vol. 2 No. 1 (2023): ACTA Medical Health Sciences
Publisher : ACTA Medical Health Sciences

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Abstract

Diabetes mellitus is a disease characterized by hyperglycemia. Chronic hyperglycemia indiabetes mellitus can cause various complications, one of which is diabetic nephropathy,which affects the kidney. Chronic hyperglycemia causes an increase in free radicals and adecrease in antioxidant activity resulting in oxidative stress conditions. This study aims to determine kidney damage caused by oxidative stress and the role of antioxidants in reducingthis damage through literature studies. The literature used comes from Google search results such as PubMed, Google Scholar, ResearchGate, and ScienceDirect. From the search results, ten journals meeting the inclusion and exclusion criteria were selected for review and comparison so that a conclusion could be drawn. The results of this literature study have demonstrated that biochemical parameters, such as increased levels of creatinine, urea, malondialdehyde (MDA), and decreased antioxidant enzymes, as well as kidney histological parameters, such as changes in the shape of tubules, glomeruli, and increased kidney expression, are indicators of kidney damage caused by oxidative stress. The mechanism of antioxidants in reducing kidney damage is through DNA cutting, binding to phenolic OH groups, down-regulation of the oxidase expression of nitrogen oxides 4 nicotinamide adenine dinucleotide phosphate (Nox4 NADPH), antioxidant enzyme systems, activation of the activated protein kinase pathway - silent mating type information regulation 2 homolog 1- peroxisome proliferator-activated receptor-γ coactivator 1α (AMPK-SirT1- PGC-1 α), protein glycation reactions, and inhibition of protein 53 (P53) so that erythroid nuclear factor 2-related factor 2 (Nrf2) can activate antioxidant gene transcription. 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Co-Authors Astri Pradini Desire M Nataliningrum Diana Akmalia Tatang Bisri Yanti Nurrokhmawati