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Mahral Effendi S
STIKes Senior Medan
Biochemistry, Genetics & Molecular Biology Immunology & microbiology

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Uji Aktivitas Antioksidan Ekstrak Etanol Buah Andaliman (Zanthixylum acanthopodium DC.) Dengan Metode DPPH Mahral Effendi S
Herbal Medicine Journal Vol 3 No 2 (2020): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

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Abstract

Andaliman fruit (Zanthixylum acanthopodium DC) is known to have benefits for treating intestinal tracts, treating nausea, asthma, anti-cancer, antioxidants, high blood pressure, and canker sores. The purpose of this study was to determine whether andaliman fruit has antioxidant activity with the DPPH method. The method used in this research is an experimental method, with the stages of collecting plant material, identifying samples, making simplicia, making reagents, characteristics of simplicia, screening phytochemicals, making extracts from andaliman fruit, preparing tools, testing the antioxidant activity of andaliman fruit extracts with the DPPH method. The antioxidant activity test used the DPPH method and then made a control solution and a Vitamin C solution. In this study, the DPPH solution produced a maximum wavelength of 517 nm. The results obtained showed that andaliman fruit extract had very weak antioxidant activity seen from the IC50 value, which was at a concentration of 239.061 ppm. The results of the phytochemical screening of Andaliman fruit contain secondary metabolites, namely alkaloids, flavonoids, saponins, steroids, glycosides.
Penentuan Kadar Total Flavanoid Pada Ekstrak Etanol Daun Lengkuas Merah (Alpinia purpurata K.Schum) Secara Spektrofotometri Uv-Vis Mahral Effendi S
Herbal Medicine Journal Vol 3 No 1 (2020): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

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Abstract

Galangal leaves contain essential oil of approximately 1% greenish yellow essential oil which mainly consists of 48% methyl-cinnamate, 20% - 30% cineol, eugenol, 1% camphor, sesquiterpen, δ-pinen, galangin. Galangal raw materials can produce essential oil, besides that galangal raw materials are easy to obtain and cheap, so the processing can be developed to obtain an oleoresin product by an extraction process using the MAE (Microwave Assisted Extraction) method so as to produce oleoresin products. This study aims to determine the effect of extraction time using the Microwave Assisted Extraction (MAE) method on total phenolics, flavonoids, tannins, and the antioxidant activity of red galangal oleoresin. The results showed that MAE long treatment had a significant effect (p <0.05) on all observed variables, namely phenolic levels, flavonoid levels, tannin levels and antioxidant activity. The longer the MAE time, the tended to increase the levels of the observed variables, all of the observed variables, namely the flavonoid level 0.6109 mg.QE / g.
Penentuan Kadar Senyawa Flavonoid Ekstrak Etanol Daun Kunyit (Curcuma domestica Val) Secara Spektrofotometri Uv-Vis Mahral Effendi S
Herbal Medicine Journal Vol 2 No 2 (2019): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

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Abstract

A study concerning the determination level total of flavonoid and phenolic of White Tumeric Rhizoma Extract. The purpose of this study was to determine the levels total, flavonoids and phenolics of White Tumeric Rhizoma Extract. Extraction of chemical constituents of White Tumeric Rhizoma Extract performed by maceration method using methanol until the filtrate was clear. Determination level total of flavonoid and phenolic was conducted using spectrophotometry UV-Vis. Total flavonoid was tested using a quercetin standard and total phenolic content was tested using standard gallic acid. The results were obtained with concentrations of total flavonoid is 4,8%.
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