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All Journal Herbal Medicine Journal JIKA
Andi Josep Nicolas Hutahaean
Program Studi Farmasi, Sekolah Tinggi Ilmu Kesehatan (STIKes) Arjuna Laguboti
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Profil Kromatografi Lapis Tipis (KLT) dan Uji Aktivitas Antifungi Ekstrak n-Heksan Herba Kembang Bulan (Tithonia diversifolia (Hemsl.)Gray) Terhadap Candida albicans dan Microsporum canis Heny Kurniasari; Andi Josep Nicolas Hutahaean; Uly Widya Rochmatil Ulla; Tumpal Manurung
Herbal Medicine Journal Vol 5 No 1 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.829 KB) | DOI: 10.58996/hmj.v5i1.44

Abstract

Moon flower herb is a well-known plant species that has been used as traditional medicine in Indonesia for generations. In previous studies it was known that moonflower (Tithonia diversifolia (Hemsl) Gray) had antihyperglycemic, antidiabetic, antimicrobial and antimalarial effects. Based on previous research, it is also known that the roots, stems, leaves and essential oil of moonflower (Tithonia diversifolia (Hemsl) Grey) contain alkaloids, phenolic compounds, steroids, saponins and flavonoids. The purpose of this study was to determine the activity of n-Hexan of moonflower herb against Candida albicans and Microsporum canis. This research was conducted in several stages, starting with the process of collecting and processing samples, testing the characteristics of simplicia, and maceration. Moonflower herb extract (Tithonia diversifolia (Hemsl) Grey, Thin Layer Chromatography (TLC) and antifungal activity testing. The results showed that moonflower herbs had a moisture content of about 10.2%. Thin Layer Chromatography (TLC) tested moonflower herbs against n-hexane extract containing polyphenolic compounds and steroids.The minimum inhibitory concentration (MIC) of n-hexane extract of moonflower herb against Candida albicans ATCC 10231 was at a concentration of 400 mg/mL which was 7.8 mm, while Microsporum canis at a concentration of 200 mg /mL is 7.28 mm.
HUBUNGAN KEPATUHAN PENGGUNAAN OBAT DENGAN KUALITAS HIDUP PASIEN PENDERITA HIPERTENSI DI KECAMATAN LAGUBOTI KABUPATEN TOBA Andi josep Nicolas Hutahaean; Meliani Dwi Lestari; Harsan Arifin Kasan; Janly Pangaribuan
Jurnal Ilmu Kesehatan Abdurrab Vol. 2 No. 4 (2024): Volume 2 Nomor 4 Desember 2024
Publisher : LPPM Universitas Abdurrab

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Abstract

Hypertension is a "silent killer" which is generally known by the public as high blood pressure. Hypertensive patients who do not undergo long-term medication therapy will cause complications and discomfort so that it will affect the quality of life. This condition can be prevented and overcome by routine drug therapy. The purpose of this study was to determine the relationship between drug compliance and the quality of life of hypertensive patients in Laguboti District, Toba Regency. This research method is a cross-sectional survey, a correlation study to find a relationship between risk factors (independent) and their effects or influences (dependent). The sample in this study consisted of 42 hypertensive patients in Simatibung Village and Op. Raja Hutapea Timur Village. Data collection used a simple cluster random sampling technique. The data analysis technique used was the Spearman test. This study states that drug compliance in hypertensive patients states that 52.4% have moderate compliance with a quality of life level of 59.5% have a high quality of life. Based on the results of the Spearman test, the results. Sig. Value. (2-tailed) is 0.736 > 0.05, it can be concluded that there is no significant correlation between drug compliance and quality of life. This study is expected to improve drug compliance and quality of life.
Co-Authors Harsan Arifin Kasan Heny Kurniasari Janly Pangaribuan Meliani Dwi Lestari Tumpal Manurung Uly Widya Rochmatil Ulla