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All Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia
Ninik Mudjihartini
Departemen Biokimia dan Biologi Molekuler, Fakultas Kedokteran, Universitas Indonesia, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Public Health

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Peptida Antimikrobial Cathelicidin dan Hubungannya terhadap Vitamin D dalam Masa Pandemi COVID-19 Natasha Dianasari Devana; Ninik Mudjihartini
Majalah Kedokteran Indonesia Vol 72 No 6 (2022): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.72.6-2022-923

Abstract

A peptide known as antimicrobial peptide (AMP) possesses antimicrobial effects against bacteria, fungus and viruses. AMP, also known as Host Defense Protein (HDP), is one of the body's defense mechanisms since it has the capacity to actively kill viruses. When it comes to respiratory cells, which are the major target of the SARS CoV-2 virus that produces COVID-19, cathelicidin, a kind of AMP in humans, is known to have protective properties. Cathelicidin AMP performance represents the first-line action of the natural immune system, with cathelicidin synthesis linked to appropriate vitamin D levels. Numerous earlier studies have discovered a connection between low cathelicidin levels and low vitamin D levels; this underlines the significance of vitamin D levels in strengthening the immune system. Naturally, particularly for the production of cathelicidin, which serves as the body's primary line of defense during the COVID-19 pandemic.
Co-Authors Natasha Dianasari Devana