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All Journal Jurnal Ilmiah Kedokteran Wijaya Kusuma
Made Subawa Harsa, Made Subawa
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

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EFFECT OF INTAKING HIGH-FAT DIET ON WHITE RAT’S (Rattus norvegicus) BLOOD LIPID PROFILE Harsa, Made Subawa
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 3, No 1 (2014): Edisi Maret 2014
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

Obesity and metabolic syndrom are characterized by dislipidemia. One of methods that is performed to increase body fat contents is by intaking of high-fat diet. The purpose of this study was to demonstrate the effect of a dietary intake of high-fat on the lipid profile (total cholesterol, HDL, LDL, and triacylglycerol) in white rat (Rattus norvegicus). This research was tested on 30 white rats that were divided into 2 randomized groups, and were treated for 4 weeks. Group 1 (K1) : was treated with standard diet, (K2) : with standard and high-fat diet. The results showed that intaking high-fat diet increases the total cholesterol content, triacylglycerol, LDL cholesterol, and decreases HDL cholesterol content.
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