Chaula Putri Rizkia
Departemen Ilmu Gizi, Fakultas Kedokteran, Universitas Indonesia, Jakarta, Indonesia

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Peran Probiotik Terhadap Kadar Zonulin pada Penderita Obesitas Chaula Putri Rizkia
Majalah Kedokteran Indonesia Vol 73 No 2 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.2-2023-964

Abstract

The prevalence of obesity is increasing worldwide and is considered as epidemic. According to the 2018 Riskesdas data, the obesity rate in Indonesia has increased to 35.4% compared to 2007. Obesity is a risk factor for metabolic diseases due to chronic inflammatory conditions. This is associated with increased permeability of the intestinal wall which is characterized by increased levels of zonulin. Probiotics are known to reduce zonulin levels and improve intestinal integrity in obesity.