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Heru Fajar Trianto
Fakultas Kedokteran, Universitas Tanjungpura Pontianak
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Gambaran Histologikorteks Serebri Tikus Putih (Rattus norvegicus) Jantan Galur Wistar Setelah Penghentian Pajanan Monosodium Glutamat (MSG) Muhammad Hadi Arwani; Heru Fajar Trianto
Jurnal Vokasi Kesehatan Vol 1, No 6 (2015): November 2015
Publisher : Poltekkes Kemenkes Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.598 KB) | DOI: 10.30602/jvk.v1i6.34

Abstract

Abstract: Histology Of Cortex Celebrity Male Wistar Rats (Rattus norvegicus) After Cessation Exposure Of Monosodium Glutamate (MSG). The aim of this study was to determine the reparation or the regeneration pyramidal cells in cortex after cessation exposure of MSG. This is an experimental study used 27 male Wistar rats and divided into 3 large groups (K(+), K(-), and P). The variables data was observed in the tenth field of view the cortex celebrity with a magnification of 40x objective lens and the data was determined the average of it. Data were analyzed using Kruskal Wallis followed by Mann Whitney. Results show that the Exposure to MSG for a minimum of 28 days resulted from no significant change (p>0,05) in the account of normal pyramidal cells and the account of damaged pyramidal cells.Abstrak : Gambaran Histologikorteks Serebri Tikus Putih (Rattus norvegicus) Jantan Galur Wistar Setelah Penghentian Pajanan Monosodium Glutamat (MSG). Penelitian ini bertujuan untuk mengetahui adanya perbaikan atau regenerasi sel piramidal di korteks serebri setelah penghentian pajanan toksik MSG pada tikus. Penelitian ini merupakan penelitian eksperimental menggunakan 27 ekor tikus jantan galur wistar yang dibagi menjadi 3 kelompok besar (K(+), K(-), dan P). Data diamati pada 10 lapang pandang korteks dengan perbesaran lensa objektif 40x dan dicari reratanya. Data kemudian dianalisa menggunakan uji Kruskall Wallis yang dilanjutkan dengan Mann Whitney Test. Hasil penelitian menunjukkan bahwa pajanan MSG selama minimal 28 hari tidak mengakibatkan perubahan secara signifikan (p>0,05) jumlah sel piramidal normaldan jumlah sel piramidal rusak.
Histologi Sel Pyramidal Hipokampus Tikus Putih Pasca Penghentian Pajanan Monosodium Glutamate Peroral Buddy Dayono; Heru Fajar Trianto; M. In’am Ilmiawan
Jurnal Vokasi Kesehatan Vol 1, No 4 (2015): Juli 2015
Publisher : Poltekkes Kemenkes Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (255.227 KB) | DOI: 10.30602/jvk.v1i4.26

Abstract

Abstract: Histology Of Hippocampal Pyramidal Cells Rats After Cessation Of Oral Administration Monosodium Glutamate. The aim of this study was to determine the histological of hippocampal pyramidal cells adult male Wistar rats (Rattus norvegicus) after cessation of oral administration monosodium glutamate. This is true experimental study. This study used 27 rats and divided into 9 groups with simple random sampling. Data were analyzed using One-way ANOVA followed by LSD and Kruskal Wallis Test followed by Mann-Whitney Test. There were no significant differences in the mean number of pyramidal cells degeneration between treatment groups (P) (p≥0,05). There were significant differences in the mean number of normal pyramidal cells between treatment groups (P) (p<0,05).Abstrak : Histologi Sel Pyramidal Hipokampus Tikus Putih Pasca Penghentian Pajanan Monosodium Glutamate Peroral. Penelitian ini bertujuan untuk mengetahui gambaran histologis sel piramidal hipokampus tikus putih (Rattus norvegicus) jantan dewasa strain wistar pasca penghentian pajanan MSG peroral. penelitian ini menggunakan desain true experiment. Penelitian ini menggunakan 27 tikus dan dibagi 9 kelompok. Sampel dipilih dengan metode simple random sampling. Data dianalisa menggunakan one-way anova dilanjutkan LSD dan Kruskal Wallis Test dilanjutkan Mann-Whitney Test. Hasil menunjukkan bahwa tidak ada perbedaan bermakna rerata jumlah sel piramidal rusak pada seluruh kelompok perlakuan (P) pada hari yang berbeda (p≥0,05). Terdapat perbedaan bermakna rerata jumlah sel piramidal normal pada seluruh kelompok perlakuan (P) pada hari yang berbeda (p<0,05). 
Co-Authors Buddy Dayono M. In’am Ilmiawan Muhammad Hadi Arwani