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All Journal Journal of General Procedural Dermatology and Venereology Indonesia
Regalado-Morales, Eileen
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Medicine & Pharmacology

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Cutaneous manifestation of thyroid carcinoma in a 64-year-old Filipino woman: a case report Linata, Andrean; Carpio, Benedicto dL; Regalado-Morales, Eileen
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 6, No. 1
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Background: Cutaneous metastasis is a rare phenomenon of thyroid carcinoma. Several mechanisms regarding cutaneous metastasis from internal malignancies have been proposed. Various treatment options are available, including surgical procedures, radioiodine therapy, thyroid hormone therapy, and other possible therapies. The prognosis of thyroid carcinoma with cutaneous manifestation is poor.Case Illustration: We presented a case of 64-year-old female patient with previously diagnosed thyroid carcinoma admitted with enlarged and tender nodules on the right side of the anterior neck. No surgical intervention was done and patient was treated with chemotherapy using doxorubicin 80 mg as the agent of choice. Levothyroxine 100 mcg was also administered every 24 hours. Chemotherapy was given, however the patient eventually died due to respiratory failure.Discussion: The patient initially presented with a slow-growing neck mass, which rapidly developed into larger mass with multiple erythematous to violaceous papules, firm tender nodules, and patches on the thoracic area, indicating slow and rapid progression of the disease. According to histopathologic examination, the patient had papillary thyroid carcinoma. However, the patient poorly responded to the chemotherapy regimen with doxorubicin, which indicated that this malignancy is associated with poor prognosis.Conclusion: Cutaneous metastasis is a rare complication of thyroid carcinoma. Typically, it initially develops as a slow-growing tumor that subsequently progresses into multiple malignant lesions. It is an indicator of poor prognosis in thyroid carcinoma, and further studies are warranted to improve the prognosis of this disease
A 61-year-old Filipino man with lichen planus concomitant with cicatricial alopecia, mimicking discoid lupus erythematosus Harris, Lie Michelle E.; Carpio, Benedicto dL; Regalado-Morales, Eileen; Guzman, Amelita Tanglao-De; Lapitan-Torres, Armelia
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 2
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Background: Lichen planus (LP) is an idiopathic inflammatory disease affecting the skin, mucous membranes, hair, and nails. Even though rare, LP may also present as cicatricial alopecia or a condition referred to as lichen planopilaris (LPP). On the other hand, lupus erythematosus (LE) is an autoimmune disorder with a possibility of systemic involvement. Classical discoid lupus erythematosus (DLE) is the most common form of LE and has a hallmark of scarring alopecia. Case Illustration: A 61-year-old Filipino man presented with a 7-month history of persistent multiple erythematous hairless scarring plaques on the scalp with multiple erythematous–violaceous to hyperpigmented atrophic plaques on the face and distal upper extremities. Discussion: The remarkable atrophic scarring alopecia on the scalp, along with the atrophic coin-shaped plaques on the face and extensor aspects of both forearms on this patient, brought DLE as the initial clinical impression. Besides cicatricial alopecia being a prevalent feature of DLE, the noticeable scarring alopecia on the scalp with the concomitant appearance of multiple atrophic skin lesions on sun-exposed areas supported this reasoning. Nevertheless, the skin punch biopsy of this patient showed numerous histopathological features of LP. Conclusion: LP can present with several morphological cutaneous presentations, including atrophic LP, which may mimic cutaneous DLE. Even though LP is a non-scarring disease, a follicular variant of LP, LPP has a distinct clinical and histologic entity with associated scarring alopecia. The presence of atrophic cutaneous LP concomitant with scalp LPP may mimic DLE clinically.
Co-Authors Carpio, Benedicto dL Guzman, Amelita Tanglao-De Harris, Lie Michelle E. Lapitan-Torres, Armelia Linata, Andrean