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Pengembangan Formulasi Sediaan Gummy Candy dengan Variasi Konsentrasi Gelatin Sebagai Gelling Agent Vriezka Mierza; Shinta Puspa Dwiyanti; Mulidini Mulidini; Salsabila Granadha Nibullah; Zuyyinna Alya Abbas
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.641 KB) | DOI: 10.36490/journal-jps.com.v6i2.102

Abstract

Gummy candy is candy that is usually made from fruit juice or water and a gelling agent, has a clear, transparent appearance and has a chewy texture. The purpose of this study was to determine the formulation and compare the levels of gelatin as a gelling agent in the formation of a gummy candy chewy texture. The research method used was to conduct a literature study on several credible journals with criteria for journals in the last 10 years regarding the formulation of gummy candy with gelatin as the gelling agent. The results obtained are the use of gelatin as a gelling agent that can be combined with pectin and glycerin. The best concentration of the combination of gelatin and pectin is in the range of 15-20%, while the best concentration of the combination of gelatin and glycerin is in the range of 25-30%. So it can be concluded that the use of gelatin as a gelling agent and pectin as a chewiness enhancer requires a lower concentration compared to gelatin and glycerin to produce gummy candy which has the preferred level of elasticity.
Analisis senyawa acetaminophen dalam sampel biologis dengan berbagai macam metode Lina Nurfadhila; Marsah Rahmawati; Nur Komala fitri; Salsabila Granadha Nibullah; Welly Windari
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.197

Abstract

Acetaminophen or Paracetamol is a compound that has pharmacological effects as an analgesic and antipyretic. The purpose of this journal review is to identify and understand the various methods that can be used to analyze biological samples of patients when taking paracetamol through their biological samples. The initial process for carrying out the analysis is to carry out sample preparation, samples are prepared by various suitable methods such as liquid-liquid extraction methods, solid phase extraction (SPE) and protein precipitation methods, then samples will be analyzed using appropriate methods. instruments such as GC-MS, LLE, LC-MS, HPLC-MS, or UHPLC-MS. Of the several instruments used the HPLC-MS method is the most effective method for analyzing biological samples, because HPLC-MS is considered fast, selective and sensitive and has the lowest LLOQ quantification value or lower limit.