Salman Salman
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa Karawang

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Pengaruh Gaya Hidup Sehat Terhadap Kesehatan Mental Remaja Elsya Martia; Salman Salman
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (203.369 KB) | DOI: 10.36418/syntax-literate.v7i11.9810

Abstract

Penelitian ini bertujuan untuk melihat pengaruh gaya hidup sehat terhadap Kesehatan mental remaja. Metode yang digunakan pada review ini merupakan suatu tinjauan literature (literature review) terhadap sepuluh jurnal berdasarkan teori-teori yang relevan. Hasil uji setelah dikomposit 6 variavel diatas, sebagaian besar remaja memiliki gaya hidup sehat (71, 84%) dan gaya hidup tidak sehat (26,72%). Setelah dikomposit 3 variabel diatas, sebanyak 9,4% remaja memiliki gangguan kesehatan mental dan mayoritas remaja tidak mengalami gangguan kesehatan mental (90,6%). Sebanyak 32,9% responden mengalami depresi dengan memiliki keadaan psikososial yang tergangu. Dari hasil uji hubungan didapatkan nilai P value sebesar 0,000 dimana nilai ini (2-sided) < 0,05. Simpulan, Adanya hubungan yang signifikan antara pengetahuan tentang gaya hidup sehat dengan perilaku gaya hidup sehat serta ada hubungan antara sikap terhadap gaya hidup sehat dengan perilaku gaya hidup sehat.
Kemanan Obat Biosimilar Trastuzumab dan Pertuzumab untuk Penyakit Kanker Payudara HER-2 Positif: Literature Review Fikri Aldebaran Azizi; Salman Salman
Jurnal Sehat Mandiri Vol 19 No 1 (2024): Jurnal Sehat Mandiri, Volume 19, No.1 Juni 2024
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v19i1.1387

Abstract

A biosimilar is a biological product that is similar to the original reference product in terms of safety, purity, efficacy, with no clinically significant differences. Breast cancer is a dangerous disease that still claims the lives of many women in the world, which requires effective treatment to improve patient prognosis. With biosimilar treatment alternatives, it is important to evaluate their safety and effectiveness. This makes biosimilars convenient for patients who lack the high cost of cancer treatment. The analysis showed that the biosimilar drugs trastuzumab and pertuzumab had consistent performance and comparable efficacy to the reference drugs. The purpose of this article is to provide insight into the comparison of safety and effectiveness of trastuzumab and pertuzumab biosimilars against HER2-positive breast cancer with the reference product. The method used is a qualitative method by analyzing 10 articles that meet the eligibility of 1,405 literature found in PubMed. The conclusion of this literature review is that biosimilar pertuzumab and trastuzumab have good safety and effectiveness and are similar to their reference patent products. Although it has side effects such as nausea, thrombocytopenia, diarrhea and anemia. Which if combined with other drugs can add to the survival of patients and have an effect.