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All Journal Majalah Kedokteran Bandung Jurnal Kesehatan Masyarakat
Heru Wijono
Faculty of Medicine, University of Surabaya
Education Medicine & Pharmacology Public Health

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Drug Interactions in Diabetic Ulcer Patients in an Indonesian Private Hospital Finny Alifiyatur Roosyidah; Rika Yulia; Fauna Herawati; Heru Wijono
Majalah Kedokteran Bandung Vol 55, No 2 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n2.2982

Abstract

Diabetic ulcers can progress into tissue death, or gangrene, which create a risk for amputation. Measures for preventing other complications and accelerating wound healing in diabetic ulcers include blood sugar level control, diet adjustment, wound care, antidiabetic drug administration, and comorbid therapy. This leads to the use of various drugs that can potentially trigger drug interactions. This study aimed to identify possible drug interactions in the therapeutic management of diabetic ulcer patients treated in Husada Utama Hospital Surabaya, Indonesia, from January 2020–June 2022. This was a descriptive observational study using retrospective data from medical records. Results showed that 103 types of drugs were administered to 48 research samples with 41 of them experienced drug interactions (n=263 cases). Based on the severity of drug interactions, 31 cases were categorized as major cases (11.79%), with drug-class antibiotic-antiemetic interactions as the most frequent interactions. This study proves that it is essential for doctors and pharmacists.
Demographic Factors and BMI on Declined Lung Function and Vitamin D Levels in Active Smokers Pandu Laksono; Amelia Lorensia; Heru Wijono
Jurnal Kesehatan Masyarakat Vol. 21 No. 1 (2025)
Publisher : Universitas Negeri Semarang in collaboration with Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI Tingkat Pusat) and Jejaring Nasional Pendidikan Kesehatan (JNPK)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v21i1.4547

Abstract

Cigarettes are one of the causes of health problems in the world. Smoking has been known to have a direct impact on reducing lung function. Smoking increases the risk of vitamin D deficiency. Vitamin D is a vital nutrient as a lung immunomodulator. Deficient levels will cause problems with lung health, especially in active smokers. This cross-sectional research using multivariate path analysis and the SEM-PLS method has three objectives. The direct influence of three independent variables, including obesity, smoking, and demographics. Regarding vitamin D status and lung function, analyzing the direct effect of vitamin D on lung function, and thirdly, analyzing the indirect one of the three independent variables on lung function through vitamin D levels. This research took time from October 2023 to January 2024 and involved 47 active smoker respondents whose vitamin D level status and lung function were measured. There was a significant direct effect of obesity level on vitamin D levels in the active smoker population (p<0.05;f-square=2.889). While demographic factors (p>0.05;f-square=0.030) and smoking frequency (p>0.05;f-square=0.003) did not have a direct significant effect. Demographic factors, obesity, and smoking frequency don’t have significant direct effect on lung function in active smokers (p>0.05).
Co-Authors Amelia Lorensia Fauna Herawati Finny Alifiyatur Roosyidah Pandu Laksono Rika Yulia