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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Raihan Fatihka Devi
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Relationship of genetic factors to the degree of Acne vulgaris as one of the predisposing factors in student Faculty of Medicine University of Muhammadiyah Malang Dwi Nurwulan Pravitasari; Ratna Wulandari; Sri Adila Nurianiwati; M Yuliansyah Aldi Kurniawan; Raihan Fatihka Devi
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 7 No 2 (2023): Journal Qanun Medika Vol 07 No 02
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v7i2.17145

Abstract

Acne vulgaris is a skin disease, a chronic inflammation that affects the poly sebaceous glands, especially on the face and neck. One of the endogenous causes that influence the occurrence of acne vulgaris is a genetic and hormonal predisposition. Family history of acne is one of the risk factors in family genetics associated with the onset of the disease, the difficulty of therapy, and the risk for relapse. This research aimed to explain the relationship between genetic factors to the degree of acne vulgaris as one of the predisposing factors. This research was observational analytic, using purposive sampling as the sampling method and collecting data using a cross-sectional questionnaire. Statistical analysis between variables shows that age was not related (p = 0,790), while gender was not related (p = 0,066), the father's genetic history was related (p = 0,001), and mother's genetic history was not related (p = 0,390). In conclusion, among the factors that were analyzed, the father's genetic history was the only one which has a relationship in aggravating the degree of acne vulgaris.
Factors Abssociated With Occupational Irritant Contact Dermatitis In Cleaning Service Dwi Nurwulan Pravitasari; Raihan Fatihka Devi; Probo Yudha Pratama Putra
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 2 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i2.34815

Abstract

Occupational contact dermatitis is one of the occupational diseases which often arises due to contact with materials in the work environment. Cleaning service (CS) is an example of a job exposed to daily irritants that can cause skin irritation. The study used an analytic observational method with a cross-sectional approach. The population of CS throughout the University of Muhammadiyah Malang is 42 people with simple random sampling. The research data used a questionnaire from the Health and Safety Executive UK (HSE UK). The analytical technique used is the Fisher Exact and Kruskal Wallis test (alternative chi-square) in the bivariate test and logistic regression in the multivariate test. Bivariate analysis showed there was no specific relationship between the length of work (p= 0.178), duration of exposure (p= 0.068), and length of exposure (p= 1,000) in CS employees at the University of Muhammadiyah Malang, while in multivariate analysis it was not influenced by the same effect, significance (sig wald duration of exposure 0.851 and length of work 0.070). The incidence of occupational contact dermatitis caused by irritants often occurs after exposure, so there is no conclusion on the length of work, duration of exposure, and length of exposure.
Co-Authors Dwi Nurwulan Pravitasari M Yuliansyah Aldi Kurniawan Probo Yudha Pratama Putra Ratna Wulandari Sri Adila Nurianiwati