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All Journal Jurnal Keperawatan Respati Yogyakarta
Januar Rizqi
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Health Professions Nursing

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THE EFFECTIVENESS OF INDONESIAN HONEY STIMULATE FIBROBLAST CELL VIABILITY AND MIGRATION THAT COULD POTENTIAL PROMOTE WOUND HEALING Januar Rizqi; Akbar Satria Fitriawan; Ririn Wahyu Widayati
Jurnal Keperawatan Respati Yogyakarta Vol 9 No 1 (2022): JANUARY 2022
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35842/jkry.v9i1.652

Abstract

Wound healing is a complex event involving both cellular and molecular activities. Fibroblasts play an important role and are keys to wound healing through cell proliferation and migration. Honey has anti-microbial, anti-oxidant, anti-inflammatory properties, which are used for various benefits such as wound healing. This study aims to explore the effect of honey on the viability and migration ability of fibroblast cells. The method used is the viability test using the MTT Assay calculated by the formula for the percentage of cell viability. Migration test using In Vitro Wound Scratch Assay. The results of the migration test images were analyzed using ImageJ. Giving honey doses of 0.5% and 0.1% increased cell viability and migration after 24 hours of intervention. Decreased cell viability after 48 hours of treatment, but there was a difference in the meaning of honey 1%, 0.5%, and 0.1% compared to control. Honey doses of 1%, 0.5%, and 0.1% increased fibroblast cell migration compared to control. The lowest honey increases the viability and migration of fibroblasts so that the possibility of wound healing. Keywords: Honey; Fibroblast Migration; Wound Scratch Assay; Wound Healing
Ginger and Warm Water Compress Reduce Complaints of Lower Back Pain in the Elderly in Gaura Village, West Sumba District, Indonesia Januar Rizqi; Christina L. Ammakiw; Nazwar Hamdani Rahil; Agustinus Nunu; Melanie Reboldera Adolfo
Jurnal Keperawatan Respati Yogyakarta Vol 10 No 2 (2023): MAY 2023
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35842/jkry.v10i2.740

Abstract

Low back pain is among the most frequent causes of discomfort in older adults. Non-pharmacological treatments for patients with low back pain include ginger and heated compresses, which provide a warming sensation and dilate blood vessels to alleviate pain. Objective: to compare the efficacy of ginger and tepid compresses on complaints of lower back pain among older people in Gaura Village, the Gaura Health Center's service area. This study employs a quasi-experimental design with a pre-and post-test. The population of this survey consisted of over-60-year-old residents of Gaura Village, with 17 participants in each group. The sampling technique used consecutive sampling. Independent t-test analysis of the differences between the two variables. The average lower back pain scale before the ginger compress was 6.82, while it was 6.12 before the heated compress. Ginger compression yields an average of 3.82, while mild compression yields 3.82. Ginger compresses alleviate low back pain in older people in Gaura Village, the Gaura Health Center's service area (p-value = 0.000). Warm compresses help lower back discomfort in elderly residents of Gaura Village, where the Gaura Health Center is located (p-value = 0.000). -value 0.167. Ginger and warm compresses can alleviate lower back discomfort in older people in Gaura Village, where the Gaura Health Center is located.
Co-Authors Agustinus Nunu Akbar Satria Fitriawan Christina L. Ammakiw Melanie Reboldera Adolfo Nazwar Hamdani Rahil Ririn Wahyu Widayati