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Leiomyoma Ablation with Transvaginal Ultrasonography-Guided Radiofrequency: A Report of Four Cases : Ablasi Mioma dengan Radiofrekuensi Terpandu Ultrasonografi Transvaginal: Laporan Empat Kasus Doddy Sutanto; Ery Surya Sevriana; Rukmono Siswishanto; Lydia Olivia; Rahmalina
Indonesian Journal of Obstetrics and Gynecology Volume 11 No. 3 July 2023
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v11i3.1834

Abstract

Abstract Objective : To perform transvaginal ultrasound-guided radiofrequency ablation (RFA) to four women with symptomatic subserous and intramural leiomyomas using standard protocols. Methods : A report of four cases. Case : This article reports three of four women with leiomyomas had heavy menstruation bleeding. The first case was a premenopausal woman with pelvic discomfort. In the second case, the patient underwent curettage after being diagnosed with a blighted ovum, the third case with non-cyclic pain and irregular cycles, and the fourth case with 14-year-old infertility and repeated IVF failure. No significant side effects or complications occurred after treatment and during observation. Monitoring uterine leiomyoma size for one week and three months showed an average reduction of 56.9%, indicating a significant reduction in myoma volume. The reported symptoms also improved. Conclusion : Transvaginal ultrasound-guided radiofrequency ablation is an effective, non-invasive therapy with minimal side effects, so it may be the primary choice for leiomyoma therapy. Keywords : Leiomyoma, RFA, transvaginal ultrasonography Abstrak Objektif : Untuk melakukan radiofrekuensi ablasi (RFA) terpandu ultrasonografi transvaginal pada empat wanita dengan mioma intramural dan suberosa bergejala dengan menggunakan protokol yang standar. Metode : Laporan empat kasus. Kasus : Melaporkan tigas dari empat wanita dengan mioma uteri mengalami perdarahan menstruasi yang banyak. Kasus pertama adalah seorang wanita premenopause dengan keluhan rasa tidak nyaman pada panggul. Pada kasus kedua, pasien menjalani kuretase setelah didiagnosis dengan blighted ovum, kasus ketiga dengan nyeri non-siklus dan siklus tidak teratur, dan kasus keempat adalah infertilitas 14 tahun dan kegagalan IVF berulang. Tidak ada efek samping yang berarti atau komplikasi yang terjadi setelah tindakan dan selama pemantauan. Pemantauan ukuran mioma uteri selama satu minggu dan tiga bulan menunjukkan penurunan rata-rata sebesar 56,9%, menunjukkan penurunan volume mioma yang signifikan. Gejala-gejala yang dilaporkan juga mengalami perbaikan. Kesimpulan : Radiofrekuensi ablasi terpandu ultrasonografi transvaginal merupakan terapi non-invasif yang efektif dengan efek samping minimal, sehingga dapat menjadi pilihan utama untuk terapi mioma uteri. Kata kunci : Mioma, RFA, ultrasonografi transvaginal
Decoding Climate Teleconnections: An Asymmetric Time-Lag Analysis of the Oceanic Niño Index and Chikungunya Dynamics in Indonesia, 2013–2023 Yonatan Yolius Anggara; Ery Surya Sevriana
International Journal of Geography, Social, and Multicultural Education Vol. 4 No. 2 (2026): 1 October 2026
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/ijgsme.v4n2.p55-64

Abstract

Raw macro-climatic and epidemiological time series are inherently prone to non-stationary biases and linear seasonal trends, causing spurious correlations that mask genuine environmental teleconnections. This study aimed to evaluate and measure the long-distance relationship between the global Oceanic Niño Index (ONI) and local Chikungunya virus (CHIKV) transmission dynamics in Indonesia from January 2012 to December 2023 (n = 144 months). Methodologically, a quantitative associative time-series design was employed within RStudio. Both datasets exhibited non-normal distributions (p=0.000) and raw non-stationarity via Augmented Dickey-Fuller testing (p>0.05). To eliminate mathematical bias, a first-order differencing transformation was applied, successfully achieving stationarity (p=0.0100). The Cross-Correlation Function (CCF) was then calculated across an interaction window from Lag -6 to Lag +6 months. The results revealed a highly dynamic double-peak epidemiological pattern, peaking in 2013 (15,324 cases) and 2023 (6,049 cases). While no instantaneous correlation occurred at Lag 0 (r=-0.0180), a significant, optimal positive cross-correlation emerged at Lag -6 (r=0.1246). This confirms an asymmetric teleconnection where an increase in the ONI—shifting toward an El Niño phase—preceding the current period by six months directly drives increased Chikungunya outbreaks in Indonesia, providing a vital baseline for climate-based Early Warning Systems.