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Legiran
Universitas Sriwijaya
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PEMAHAMAN METODE PENELITIAN BERBASIS EVIDENCE BASED PRACTICE IN NURSING PADA MAHASISWA KEPERAWATAN Lilik Pranata; Legiran; Vincencius Surani; Keristina ajul; Ketut Suryani; Aniska Indah Fari
Jurnal Kesehatan dan Pembangunan Vol 13 No 26 (2023): Journal of Health and Development
Publisher : LPPM STIKes Mitra Adiguna

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52047/jkp.v13i26.247

Abstract

Evidence-based practice in nursing is a method used to combine research results with clinical experience and values believed by patients and their families in nursing actions that aim to improve the results of nursing care for patients. Students should also be able to apply and have good knowledge of the concept of Evidence-based Practice in nursing in providing comprehensive nursing care, in order to accelerate the patient's healing process. The aim is to determine the understanding of research methods based on evidence-based practice in nursing in nursing students. This research is a descriptive survey research. The research was conducted in May 2023 and the sample in the study was nursing profession students in one of the health education in Palembang city, with a total sample of 41 active students who served in the hospital. the results showed that students' understanding of Evidence-based Practice In nursing with a good categorical as many as 2 people (5%), enough 17 people (42%) and less 22 people (51%). Conclusion, the results indicate the need for assistance to students so that students understand about Evidence-based Practice In nursing. Suggestions for health education institutions provide intensive assistance to students who are committed to applying Evidence-based Practice in nursing.
Improvement IL -10 and Reactive Oxygen Species (ROS) in HIV patients : Narrative Review Indra Franajayakk; Legiran; Eddy Mart Salim; Zen Hafy
Jurnal Kesehatan - STIKes Prima Nusantara Vol 16 No 1 (2025): Jurnal Kesehatan Volume 16 Nomor 1 Tahun 2025 (on progress)
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35730/jk.v16i1.1234

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Background: Infection Human Immunodeficiency Virus (HIV) is still become problem scary health​ for world community . This virus infection causes a bunch symptom disease characterized by with weakening system immunity body . A collection of symptoms This known with designation Acquired Immune Deficiency Syndrome (AIDS). Consequence the decline system immunity , HIV sufferers will prone to For caught various disease infections that can have fatal consequences. Objective: For know How improvement IL-10 and Reactive Oxygen Species (ROS) levels in HIV patients . Research methods: This use Narrative Review design . Articles searched from Google Scholar, PubMed, Science Direct, and EMBASE/ Elviser with use relevant keywords , then chosen based on criteria that have been set , and objectives study . Results: Increased levels of IL-10 and Reactive Oxygen Species (ROS) in patients results in a decrease in the immune system, this is characterized by increased virus replication, deactivation macrophages and depletion of the number of lymphocytes, so that the progression of the infection towards AIDS can occur. Conclusion: HIV infection causes the occurrence dysfunction mitochondria and enhancement production Reactive Oxygen Species (ROS) in cells CD4 + T lymphocytes. Various viral proteins, such as the envelope proteins Gp120, Tat, Nef and Vpr , are able to increase ROS production through various different pathways. The increase in ROS that occurs can increase mRNA expression through activation Nuclear Factor Kappa B ( NFκB ), increased IL-10 mRNA expression ultimately will increase IL-10 levels
Co-Authors Aniska Indah Fari Eddy Mart Salim Indra Franajayakk Keristina ajul Ketut Suryani Lilik Pranata Vincencius Surani Zen Hafy