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All Journal IJRETINA - International Journal of Retina
Chalid Kurniawan
santosa hospital bandung central
Health Professions Medicine & Pharmacology Public Health

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SUCCESS OF INTRAVITREAL RANIBIZUMAB IN ACUTE CENTRAL SEROUS CHORIORETINOPATHY Chalid Kurniawan; Arief Kartasasmita
International Journal of Retina Vol 3 No 2 (2020): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2020.vol003.iss002.106

Abstract

Introduction: Central serous chorioretinopathy (CSC) manifests as neurosensory detachment of the macula and observation has been considered as an appropriate first-line approach. Active treatment is required to prevent recurrences or chronic type. This study aim to evaluate the effectiveness of intravitreal ranibizumab injection (IVRI) for acute CSC. Methods: A single-center retrospective descriptive study. Five files of the patients who had the diagnosis of CSC then treated with IVRI between 2018 and 2019 have been investigated. IVRI were given once every 4 weeks until sub-retinal fluid resolved. Demographic details, best-corrected visual acuity (BCVA), and central macular thickness (CMT) were studied before and after treatment. Results: The mean age of the patients was 57 years (SD= 10.5 years) mostly female (3 patients). The mean duration before treatment was 3.8 weeks (SD= 1.4 weeks). The mean number of IVRI was 1.4 (SD= 0.5). The mean CMT before IVRI was 436.4 μm (SD= 109.1) and decreased to 243 μm (SD= 38.3) at the last visit. The mean BCVA before IVRI was 0.56 logMAR (SD= 0.37) and improved to 0.22 logMAR (SD= 0.29) Conclusion: IVRI appeared to be effective treatment for acute CSC. The mean CMT decreased and BCVA improved after therapy.
The Burden of Premature Vision Loss: Working-Age Vulnerability to Proliferative Diabetic Retinopathy in Indonesia chalid kurniawan; Mochamad R Budiman; Nadia S Athiyyah
International Journal of Retina Vol 9 No 2 (2026): International Journal of Retina (IJRetina) - INAVRS
Publisher : Indonesian Vitreoretinal Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35479/ijretina.2026.vol009.iss002.350

Abstract

Background: Diabetic retinopathy (DR) poses a critical threat to the productive workforce in developing nations. While disease duration and hyperglycemia are established risk factors, the distinct clinical aggression of young-onset Type 2 diabetes remains under-characterized in resource-limited settings. This study aimed to identify independent predictors of Proliferative Diabetic Retinopathy (PDR), specifically evaluating the differential risk profiles between working-age and elderly patients. Methods: A retrospective cross-sectional study was conducted on 118 patients with confirmed DR (NPDR=41; PDR=77) at a tertiary eye center in Indonesia. Multivariate logistic regression was performed to determine independent predictors, adjusting for potential confounders including hypertension and gender. Results: The cohort exhibited a high prevalence of advanced disease (65.3% PDR). Multivariate analysis revealed that age ≥60 years was significantly associated with a reduced risk of PDR (aOR 0.280; 95% CI 0.098–0.803; p=0.017), indicating an approximately 3.6-fold higher risk in the working-age demographic (40–59 years). Diabetes duration ≥10 years (aOR 3.805; p=0.006) and HbA1c ≥7.2% (aOR 3.856; p=0.006) were confirmed as robust independent predictors. Conclusion: Working-age patients exhibit a significantly more aggressive disease phenotype independent of diabetes duration and glycemic control. These findings suggest that current age thresholds may underestimate risk in younger populations, supporting the need for intensified retinal screening immediately upon diagnosis for early-onset patients to mitigate the socioeconomic impact of premature blindness.
Co-Authors Arief S. Kartasasmita Mochamad R Budiman Nadia S Athiyyah