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Alya Nafis
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa Karawang, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Uji aktivitas antibakteri ekstrak daun ceremai (Phyllanthus acidus (L.) Skeels) terhadap Staphylococcus aureus Alya Nafis; Dia Septiani; Jekmal Malau
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.192

Abstract

Staphylococcus aureus is a bacterium capable of causing pneumonia. However, the frequent occurrence of antibiotic resistance necessitates the exploration of alternative plant-based antibiotics as natural antibacterial agents. This study aims to analyse the antibacterial activity and chemical compound classes in the ethanol and methanol extracts of Phyllanthus acidus (L.) Skeels leaves, commonly known as ceremai leaves, exhibit antibacterial properties. Chemical compound classes were determined using the TLC method. The 96% ethanol extract of ceremai leaves contained flavonoids, alkaloids, triterpenoids, steroids, and phenols. On the other hand, the methanol extract contained flavonoids, alkaloids, steroids, and phenols. The antibacterial activity was evaluated using the Kirby-Bauer agar diffusion method. The testing revealed that ethanol and methanol extracts of ceremai leaves at concentrations of 15%, 20%, 25%, 30%, 40%, and 50% exhibited antibacterial activity against Staphylococcus aureus bacteria. The 50% concentration showed the highest inhibition zone value, with the ethanol extract (96%) measuring 3.86 ± 0.11 mm and the methanol extract measuring 2.73 ± 0.24 mm falling into the weak category
Co-Authors Dia Septiani Jekmal Malau