Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Multidiciplinary Output Research for Actual and International Issue (Morfai Journal) Molekul: Jurnal Ilmiah Kimia
Hamzah Alfarisi
Unknown Affiliation
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Social Sciences Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Preparation and characterization of nanopowder of Acalypha hispida Leaves Extract Using Planetary Ball Milling Hamzah Alfarisi; Siti Sa'diah; Berry Juliandi; Tutik Wresdiyati
Molekul Vol 17 No 1 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.1.5601

Abstract

Acalypha hispida Burm.f. is commonly used as an ornamental plant known for pharmacological effects. The nanoscale extract increases bioavailability and bioactivity. This research aimed to produce and characterize nanopowder extract of A. hispida leaves. Powdered leaves were macerated in 96% ethanol, then was evaporated in the spry dryer. Nanopowder extract was produced using planetary ball milling at 5000 rpm in different milling times, namely 5 minutes (nanopowder A), 10 minutes (nanopowder B), and 40 minutes (nanopowder C). The nanopowder extracts were evaluated using a particle size analyzer, scanning electron microscope, and high-performance liquid chromatography. The average particle size of A. hispida crude extract was 1271 nm, and nanopowder A, B, and C respectively were 837.1 nm, 803.8, and 512.2 nm. The polydispersity index of A. hispida crude extract, nanopowder A, B, and C were 0.754, 0.696, 0.717, dan 0.612. The milling process for 40 minutes reduced the content of 5% gallic acid and 10.3% catechin. The SEM image of nanopowder C was smaller than crude extract. The best average particle size of nanopowder C (512.2 nm) and polydispersity index (0.612) were produced using PBM for 40 minutes at 5000 rpm.
LITERATURE REVIEW OF EMBRYONIC DEVELOPMENT EPIGENETICS: CHROMATIN MODIFICATION AND CELL PROGRAMMING Kamila Alawiyah; Rizki Andini Nawawi; Meillisa Carlen Mainassy; Syarinta Adenina; Hamzah Alfarisi; Sternatami Liberitera
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 5 No. 6 (2025): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.18492220

Abstract

This study aims to comprehensively examine epigenetic mechanisms in embryonic development, focusing on the role of chromatin modification and cell programming as regulators of gene expression without changes in DNA sequence. The type of study used was qualitative , with a descriptive approach through literature review, which examined scientific literature from reputable international journals such as Nature, Trends in Genetics, and The FEBS Journal published between 2015 and 2025. Data were collected through systematic searches of scientific articles using thematic and inductive analysis techniques, including theme identification, data reduction, and concept categorization. The results of the study show that DNA methylation, acetylation, and histone methylation are key factors in regulating gene expression during the zygotic genome activation (ZGA) phase and the formation of cell lineages. This process demonstrates the complex interaction between epigenetic and transcriptional factors that determine the direction of cell differentiation. In addition, similarities in epigenetic regulation principles between mammals and plants were found, indicating the conservation of biological mechanisms across species. The implications of the study " " include the development of regenerative therapies, increased effectiveness of assisted reproductive technologies, and innovations in agricultural biotechnology. In conclusion, this study confirms that epigenetics is an important layer of regulation in developmental biology that enriches our understanding of the mechanisms of life formation from the earliest stages.
Co-Authors Berry Juliandi Kamila Alawiyah Meillisa Carlen Mainassy Rizki Andini Nawawi Siti Sa'diah Sternatami Liberitera Syarinta Adenina Tutik Wresdiyati