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All Journal Innovative: Journal Of Social Science Research JOURNAL OF Pharmacy and Tropical Issues
Najah Fatihatul Arifia
Universitas Singaperbangsa Karawang
Humanities Computer Science & IT Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Other

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Perbandingan Efektivitas Dan Keamanan Obat Parasetamol Dan Topikal Analgesik Untuk Pasien Osteoarthritis Munir Alinu Mulki; Nurlia Julianti; Aurora Fatimatuz Zahro; Fathina Annajla; Choerunnisa Choerunnisa; Riska Shafira; Najah Fatihatul Arifia
Innovative: Journal Of Social Science Research Vol. 3 No. 3 (2023): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v3i3.2886

Abstract

Osteoarthritis (OA) merupakan penyakit rematik yang paling umum dialami oleh lansia dan berkaitan dengan risiko kematian paling besar daripada populasi umum. Parasetamol umumnya direkomendasikan sebagai analgesik pilihan pertama pada nyeri osteoarthritis. Selain itu, Obat antiinflamasi nonsteroid topikal (NSAID) juga memiliki efikasi dapat mengurangi nyeri pada osteoarthritis tanpa memberikan efek samping yang besar. Penulisan ini bertujuan untuk mengetahui perbandingan efektivitas dan keamanan obat parasetamol dan topikal NSAID untuk pasien osteoarthritis. Penulisan ini menggunakan metode review artikel yang dilakukan melalui penelusuran dari database Pubmed. Adapun kriteria artikel yang digunakan sebagai bahan untuk review artikel adalah artikel yang bukan merupakan publikasi review artikel dan bukan merupakan publikasi sistematik review dalam rentang 10 tahun terakhir menggunakan kata kunci (osteoarthritis) AND (paracetamol) AND (topical NSAID) NOT (review[publication type]) dan didapatkan sebanyak 16 artikel. Berdasarkan hasil yang diperoleh diketahui bahwa NSAID topikal memiliki profil keamanan yang lebih baik karena penyerapan sistemik yang lebih rendah, efek samping yang lebih kecil, efek terapeutik yang lebih cepat dan efektif dibandingkan dengan obat parasetamol.
Deteksi kandungan porcine (kandungan babi) pada suatu sampel untuk autentikasi halal: kajian beberapa metode Najah Fatihatul Arifia
JOURNAL OF Pharmacy and Tropical Issues Vol. 6 No. 3 (2026): July Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/pti.v6i3.3520

Abstract

Background: Detecting pork content in samples for halal authentication is a key aspect of ensuring the halal status of food products. Halal authentication is a crucial aspect of the food and beverage industry, particularly for people who follow certain religious beliefs. Purpose: To investigate various methods for detecting pork content in samples for the purpose of halal authentication. Method: This study outlines various methods previously investigated for detecting porcine content in samples for halal authentication purposes comparing the advantages and limitations of each evaluates the suitability of these methods regarding the practical needs of the food industry and applicable regulations, and presents recommendations that can be effectively implemented in the field to ensure the halal status of food products. Results: The detection of pork content in samples has been successfully evaluated and compared. Each method including chromatography, spectroscopy, and sensor-based techniques yields different results regarding accuracy, sensitivity, specificity, analysis time, and cost. Conclusion: The detection of porsine content is a crucial step in the halal authentication of food products. Chromatographic methods particularly HPLC (including HPLC-FLD and LC-MS) have proven to be the preferred choice due to their high sensitivity, selectivity, and low limits of detection, as well as their optimal performance when combined with chemometric analysis. Suggestion: Validation of porcine detection methods across various types of food, pharmaceutical, and cosmetic samples is necessary to ensure more accurate halal authentication results.   Keywords: Chromatography; DNA; Halal Products; Spectroscopy.
Co-Authors Aurora Fatimatuz Zahro Choerunnisa Choerunnisa Fathina Annajla Munir Alinu Mulki Nurlia Julianti Riska Shafira