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All Journal International Journal of Science and Society (IJSOC) Scientific Journal
Suyata
Universitas Sriwijaya, Palembang, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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The Relationship Between Platelet-to-Lymphocyte Ratio (PLR) and HCV RNA Levels in HCV-HIV Coinfected Patients Before and After Receiving Direct-Acting Antiviral (DAA) Therapy at Dr. Mohammad Hoesin Hospital Palembang Tiara Anggita Qurilmi; Suyata; Harun Hudari; Masagus Irsan Saleh
International Journal of Science and Society Vol 5 No 4 (2023): International Journal of Science and Society (IJSOC)
Publisher : GoAcademica Research & Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54783/ijsoc.v5i4.728

Abstract

The background described in the introduction section highlights the importance of studying the correlation between the platelet-to-lymphocyte ratio (PLR) and HCV RNA levels in these patients. This research follows an analytical correlational observational design with a cross-sectional approach. The study was conducted at the Internal Medicine Polyclinic of Dr. Mohammad Hoesin Hospital, Palembang. It involved 38 subjects who met the inclusion and exclusion criteria. The primary objective was to determine the correlation between PLR and HCV RNA levels in HIV-HCV coinfected patients receiving DAA therapy. The research findings concluded that there was a decrease in PLR and HCV RNA Viral Load levels in HIV-HCV coinfected patients after receiving DAA therapy compared to before receiving DAA therapy. The Platelet-to-Lymphocyte Ratio (PLR) was directly proportional to the quantitative HCV RNA Viral Load levels in HIV-HCV coinfected patients with a strong correlation value both before and after DAA therapy.
Alginate as an Efficacious Treatment for GERD Patients: A Literature Review Ninda Septia Yuspar; Suyata
Scientific Journal Vol. 4 No. 2 (2025): SCIENA Volume IV No 2, March 2025
Publisher : CV. AKBAR PUTRA MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56260/sciena.v4i2.201

Abstract

Gastroesophageal reflux disease (GERD) is a medical condition defined by the retrograde flow of gastric contents into the esophagus, leading to various symptoms.  The principal therapy for GERD consists of proton pump inhibitors (PPIs).  Nevertheless, PPIs demonstrate reduced effectiveness in patients with non-erosive GERD or unusual symptoms.  Alginates operate by forming a gel "raft" that floats on the gastric contents, serving as a physical barrier against reflux.  Multiple studies demonstrate that alginate is more effective than antacids in alleviating GERD symptoms and has a longer duration of action.
Co-Authors Harun Hudari Masagus Irsan Saleh Ninda Septia Yuspar Tiara Anggita Qurilmi