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All Journal Jurnal Anestesiologi Indonesia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia
Reza Ishak Estiko
Medical Education Study Program, Faculty of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia
Health Professions Medicine & Pharmacology Public Health

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The role of red-cell distribution width (RDW) and mean platelet volume (MPV) as biomarkers of community-acquired pneumonia (CAP) severity Edy Purwanto; Reza Ishak Estiko; Firdausia Rahma Putri; Linda Rosita; Rahma Yuantari
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 14, No 2, (2023)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol14.Iss2.art11

Abstract

Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality worldwide. Red-cell distribution width (RDW) and mean platelet volume (MPV) are two parameters included in complete blood count (CBC). It is simple, inexpensive, and widely available in any hospital. Many previous studies have shown that RDW and MPV can be used as supporting biomarkers for CAP, but the study in this area remains limited. This study aims to investigate the relationship between RDW and MPV with the severity of CAP and their potential as biomarkers. We conducted a scoping review of original articles using PubMed, Springer Link, Taylor and Francis, EBSCO, Cochrane Library, Google Scholar, Medline, Science Direct, Wiley, and Portal Garuda. Only articles published between 2012 and 2022 in English or Indonesian were included. Out of 11,852 articles reviewed, only 18 met the criteria for the focus on using RDW, MPV, or both as biomarkers for CAP. The details of these studies, including their research design, internal and external validity, and key results, are presented. The results show that increased RDW and MPV levels correlate with higher morbidity and mortality rates among CAP patients. Elevated levels of RDW (>14%) and MPV (>8.1 fL) can predict and acts as a biomarker of CAP severity. Thus, measuring RDW and MPV may give physicians a way to anticipate the outcomes for patients with CAP, helping them make and implement decisions, either alone or in combination with other established methods.
Pain Severity in Post-Caesarean Section and Its Preoperative Factors Derajad Bayu Atmawan; Hanifa Agung Kurniawan; Reza Ishak Estiko; Trisya Allinda
JAI (Jurnal Anestesiologi Indonesia) Publication In-Press
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.57730

Abstract

Background: According to World Health Organization (WHO), the global prevalence of cesarean section (C-section) reaches 21% of all deliveries and is expected to increase to 29% by 2030. This major surgery is associated with moderate to severe postoperative pain, which can affect postoperative recovery.Objective: This study aims to identify preoperative factors that affect post-cesarean pain with numeric rating scales 12 and 24 hours postoperative.Methods: A cross-sectional study was conducted at dr. Soehadi Prijonegoro Hospital, Sragen, Indonesia. The subject criteria are: (1) willing to participate in this study, (2) age more than 18 years old, (3) cooperative and communicative, and (4) not in disability condition. This research has conducted ethical approval by the Ethics Committee of dr. Soehadi Prijonegoro Hospital prior to the study.Results: We obtained 30 subjects, with no dropouts, aged 22 to 44 years, with 20% being older than 35 years pregnant women. Preoperative factors were multigravida, previous C-section, overweight to severe obesity, preeclampsia, fetal malposition, preterm premature rupture of the membranes, human immunodeficiency, malnutrition, preterm labor, hepatitis B, and anemia. Also, 83.3% of patients underwent emergency surgery. Most patients experienced moderate to severe pain 2 hours postoperation, and mild to moderate pain 24 hours postoperation.Conclusion: No significant correlation was found between preoperative factors and postoperative pain (p>0.05). Nonetheless, pain management should be tailored to each patient’s clinical condition.
Co-Authors Derajad Bayu Atmawan Edy Purwanto Firdausia Rahma Putri Hanifa Agung Kurniawan Linda Rosita Trisya Allinda Yuantari, Rahma