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All Journal Althea Medical Journal Acta Biochimica Indonesiana Jurnal Integrasi Kesehatan dan Sains Jurnal Info Kesehatan Global Medical and Health Communication
Mirasari Putri
Department Of Biochemistry, Nutrition And Biomelecular, Faculty Of Medicine Universitas Islam Bandung, Bandung-Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Zinc deficiency effect on clinical features of Coronavirus Disease 2019 patients: A scoping review Moch Ikhsan Juliansyah; Lisa Adhia Garina; Mirasari Putri
Acta Biochimica Indonesiana Vol. 6 No. 1 (2023): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.123

Abstract

COVID-19 was declared a pandemic in March 2020. Various therapeutic guidelines have been established for treating COVID-19, such as anti-inflammatory, antiviral therapies, and zinc supplementation. Zinc deficiency is thought to worsen the condition of patients with COVID-19 infection. However, the effect of zinc deficiency on COVID-19 patients has not been widely reported. In this scoping review, we aim to explore the impact of zinc deficiency on the clinical features of COVID-19 patients. A comprehensive search was conducted across the databases, including PubMed, ScienceDirect, Springer Link, ProQuest, and Google Scholar, using the keywords “Zinc” AND “(COVID-19 or SARS-CoV-2)”. A total of 2,458 articles published between 2019 and 2020 were screened following the PRISMA guidelines and subjected to critical appraisal. Three articles were included, focusing on the effect of zinc deficiency on the clinical features of COVID-19 patients. As of 2022, two articles reported worsening symptoms, one described an increased hospitalization duration, and one reported worsening treatment outcomes in the zinc deficiency group. This review concludes that zinc deficiency worsens symptoms, increases the duration of hospitalization, and leads to worse outcomes in COVID-19 patients.
Pengaruh Kadar Feritin Darah terhadap Status Gizi Pasien Thalasemia β Mayor Anak Namira Ramadanty; Tito Gunantara; Mirasari Putri
Jurnal Integrasi Kesehatan dan Sains Vol 5, No 2 (2023): Jurnal Integrasi Kesehatan dan Sains
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v5i2.11677

Abstract

AbstrakThalasemia merupakan kelainan hemolitik yang ditandai dengan penghancuran sel darah merah secara berlebihan. Penyakit ini diwariskan secara autosomal resesif dari orangtua yang berakibat pada kelainan sintesis rantai globin. Pasien thalasemia menjalani pengobatan dengan transfusi darah setiap bulan selama hidupnya. Pengobatan tersebut menimbulkan efek samping yang signifikan terhadap tubuh pasien. Transfusi darah yang terus menerus dapat menyebabkan penimbunan zat besi sehingga kadar feritin dalam tubuh meningkat. Selain itu, pasien thalasemia berisiko mengalami gangguan kelenjar endokrin dan anemia. Kondisi tersebut menyebabkan anak menjadi tidak mempunyai nafsu makan sehingga asupan gizi bekurang. Penelitian ini dilaksanakan di RSUD Al-Ihsan Januari–Desember 2022. Tujuan penelitian ini adalah mengetahui pengaruh kadar feritin darah terhadap status gizi pasien thalasemia β mayor anak. Metode penelitian ini, yaitu observasional analitik melalui pendekatan cross sectional. Subjek penelitian ini berjumlah 58 orang. Alat yang digunakan pada penelitian adalah grafik pertumbuhan berdasarkan The WHO Reference 2007. Hasil studi menunjukkan p=0,004 (p<0.05) dengan nilai r sebesar 0,536 yang berarti terdapat pengaruh kadar feritin terhadap status gizi pasien thalasemia β mayor anak di RSUD Al-Ihsan Kabupaten Bandung tahun 2022. Simpulan, kadar feritin darah berpengaruh terhadap status gizi pasien thalasemia β mayor anak. Effect of Blood Ferritin Levels on Nutritional Status of Pediatric Patients with Thalassemia β MajorAbstractThalassemia is a hemolytic disorder characterized by excessive destruction of red blood cells. The disease is inherited autosomal recessive from the elderly resulting in abnormalities in the synthesis of globin chains. The thalassemia patient undergoes treatment with blood transfusions every month during his lifetime. Such treatment causes significant side effects to the patient's body. Continuous blood transfusions can cause iron accumulation so that ferritin levels in the body increase. In addition, thalassemia patients are at risk of endocrine gland disorders and anemia. This condition causes the child to have no appetite, so the nutritional intake is frozen. This research was conducted at Al-Ihsan Hospital January-December 2022. This study aimed to determine the effect of ferritin levels on the nutritional status of children with β thalassemia major. This research method is analytically observational through a cross-sectional approach. The subjects of this study amounted to 58 people. The tool used in this study was a growth chart based on the 2007 WHO Reference. The analysis results showed p= 0.004 (p-value<0.05) and r value of 0.536, which means that there is an effect of ferritin levels on nutritional status of pediatric patients with thalassemia β major at Al-Ihsan Hospital, Bandung Regency in 2022. This study concludes that ferritin levels affect the nutritional status of children with β thalassemia major.
Early Metabolic Alterations and Predictors of Obesity Among Young Adults in Indonesia: Focus on Lipid Abnormalities and Cardiometabolic Risk Mirasari Putri; Eva Rianti Indrasari; Yafma Femin Helta Heriady; Rizky Suganda Prawiradilaga
Althea Medical Journal Vol 13, No 1 (2026)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v13n1.4378

Abstract

Background: The prevalence of obesity and metabolic syndrome (MetS) is rising among young adults, contributing to early cardiometabolic risk amid lifestyle transitions in Indonesia. This study examined the associations between obesity, MetS components, and body composition among Indonesian young adults.Methods: A total of 99 participants were classified based on body mass index (BMI) into normoweight (n=51) and obese (n=48) groups. Anthropometric measurements, body composition, blood pressure, and lipid profiles were assessed. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Bivariate and multivariable logistic regression analyses were performed to identify factors independently associated with obesity. Results: Obesity was significantly associated with several MetS components. Abdominal obesity was observed only in the obese group (33.3%). Hypertriglyceridemia and low HDL cholesterol were more prevalent among obese participants compared with normoweight individuals (27.1% vs. 5.9% and 51.0% vs. 31.4%, respectively). MetS (≥3 NCEP ATP III criteria) was identified in 12.5% of obese participants and was absent in the normoweight group. Multivariable analysis identified family history of hypertension (adjusted OR 2.82; 95% CI 1.06–7.48) and elevated triglyceride levels (adjusted OR 4.78; 95% CI 1.13–20.22) as independent predictors of obesity.Conclusions: Obese young adults exhibit early metabolic abnormality, particularly abdominal obesity, low HDL cholesterol, and hypertriglyceridemia. Early metabolic screening and targeted preventive strategies are important to reduce future cardiometabolic risk. 
The Relationship between Nutritional Status and Menstrual Blood Volume among Adolescent Girls at A Boarding School Qonita Luthfiah; Eva Rianti Indrasari; Yafma Femin Helta Heriady; Mirasari Putri
Global Medical & Health Communication (GMHC) Vol. 14 No. 1 (2026): Accredited Sinta 2
Publisher : UPT Publikasi Ilmiah Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v14i1.8998

Abstract

Menstruation is an essential physiological process in adolescent girls. Reflecting not only reproductive health but also overall health status. Menstrual disorders, particularly heavy menstrual bleeding (menorrhagia), are common among adolescents, with a prevalence of approximately 12–37%. Nutritional status plays a key role in menstrual health. In adolescents with overnutrition, excess body fat can increase estrogen production, which may subsequently affect the menstrual cycle, including the volume of menstrual blood. In boarding school settings, where students live under structured schedules and share dietary patterns, nutritional imbalances are common and may disrupt menstrual patterns. This study aimed to determine the relationship between nutritional status and menstrual blood volume among adolescent girls at a boarding school in Bogor, West Java,  Indonesia, in 2025. It was an observational analytic study with a cross-sectional design involving 85 adolescent girls aged 15–17 years, selected through stratified random sampling according to predefined inclusion and exclusion criteria. Primary data were obtained from menstrual pictogram forms and measurements of body mass index (BMI) and waist circumference. Data were analyzed using univariate and bivariate analyses with the chi-square test. Among the 85 participants, 35 experienced menorrhagia, including all 15 who were classified as overnutrition based on BMI, and 11 participants with increased waist circumference. Fisher’s Exact tests for both BMI and waist circumference against menstrual blood volume yielded p-values <0.001 (p<0.005), indicating a highly significant association. In conclusion, higher BMI and greater waist circumference were strongly associated with increased menstrual blood volume among adolescent girls at a boarding school in Bogor. Nutritional balance and weight control are essential to support healthy menstrual patterns in this population.
Do Virtual Race Events Improve Physical Activity Behavior? Rizky Suganda Prawiradilaga; Fajar Awalia Yulianto; Umar Islami; Mirasari Putri
JURNAL INFO KESEHATAN Vol 23 No 2 (2025): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol23.Iss2.1837

Abstract

Physical inactivity remains a major global health concern, with approximately one in four adults not meeting recommended activity levels. Virtual competitions have emerged as an alternative approach to encourage physical activity, especially following the COVID-19 pandemic. This study aimed to evaluate the impact of a virtual race event on physical activity behavior in adults with a sedentary lifestyle. A cohort study was conducted involving 68 participants, of whom 32 completed both pre- and post-event assessments. Physical activity levels were measured using the Global Physical Activity Questionnaire (GPAQ) before and four weeks after the virtual race. Participants were categorized into a sedentary group (<600 MET-minutes/week) and an active group (≥600 MET-minutes/week) based on baseline data. The McNemar test was used to assess changes in physical activity classification. Results showed that in the sedentary group, the number of active participants increased from 0 to 5 (41.67%), while in the active group, the number of participants who remained active decreased from 20 to 13 (65%). However, the difference between the groups was not statistically significant (p = 0.56). These findings suggest that while virtual race events may offer motivational value, their short-term effect on physical activity behavior may be limited without additional support mechanisms. Future studies should consider larger samples, longer follow-up periods, and the integration of behavioral strategies to enhance engagement and promote sustained physical activity, especially among previously inactive populations.                  
Co-Authors Eva Rianti Indrasari Eva Rianti Indrasari Fajar Awalia Yulianto Lisa Adhia Garina Moch Ikhsan Juliansyah Namira Ramadanty Qonita Luthfiah Rizky Suganda Prawiradilaga Rizky Suganda Prawiradilaga Tito Gunantara Umar Islami Yafma Femin Helta Heriady