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All Journal Formosa Journal of Science and Technology (FJST)
Jesviekha Ardriani Maulana
Program Studi Sarjana Terapan Kebidanan Universitas Indonesia Maju
Humanities Computer Science & IT Education Industrial & Manufacturing Engineering Social Sciences

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Physiological Changes in Mother During Pregnancy that Impact on the Pharmacokinetics and Pharmacodynamic of Drug: Literature Review Jesviekha Ardriani Maulana; Jesy Fatimah
Formosa Journal of Science and Technology Vol. 2 No. 7 (2023): July, 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v2i7.5186

Abstract

Physiological changes occurring during pregnancy can affect drug pharmacodynamics and pharmacokinetics, leading to decreased or increased drug disposition. This research uses a systematic review method or literature review. The analysis was carried out by collecting data that met the requirements and filtering based on the suitability of the article title with the research objectives to obtain relevant articles after going through the filtering stage to data extraction. The results showed that physiological changes in pregnancy induce major changes in the pharmacokinetic properties of many drugs. These changes affect the distribution, absorption, metabolism, and excretion of drugs, and thus may affect their pharmacodynamic properties during pregnancy.
Co-Authors Jesy Fatimah