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All Journal Cermin Dunia Kedokteran Jurnal Riset Multidisiplin Edukasi Cermin Dunia Kedokteran
Putu Dyah Ayu Saraswati
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Terapi Laser untuk Lesi Hiperpigmentasi Firly Clarissa Suyanto; Putu Dyah Ayu Saraswati
Cermin Dunia Kedokteran Vol 50 No 8 (2023): Dermatiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i8.757

Abstract

Seiring dengan berkembangnya teknologi, laser dan intense pulsed light (IPL) menjadi pilihan modalitas terapi hiperpigmentasi. Kedalaman penetrasi sinar laser meningkat seiring meningkatnya panjang gelombang. Laser dan IPL dengan panjang gelombang pendek efektif untuk lesi hiperpigmentasi superfisial. Sedangkan lesi hiperpigmentasi dermal dan campuran lebih merespons terhadap laser dengan panjang gelombang yang lebih panjang. Pemilihan parameter laser serta persiapan sebelum dan setelah tindakan yang tepat dapat mengurangi risiko efek samping.   With the rapid evolution of technology, laser and intense pulsed light (IPL) have become one of the modalities of choice for hyperpigmentation therapy. The depth of laser beam penetration increases with increasing wavelength. Laser and IPL with short wavelength are effective to treat superficial hyperpigmentations. While dermal and mixed type hyperpigmentations have better response towards lasers with longer wavelength. Accurate laser parameter choice and good pre and post procedural preparations reduce the risk of side effects.
Terapi Laser untuk Lesi Hiperpigmentasi Firly Clarissa Suyanto; Putu Dyah Ayu Saraswati
Cermin Dunia Kedokteran Vol 50 No 8 (2023): Dermatiologi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i8.757

Abstract

Seiring dengan berkembangnya teknologi, laser dan intense pulsed light (IPL) menjadi pilihan modalitas terapi hiperpigmentasi. Kedalaman penetrasi sinar laser meningkat seiring meningkatnya panjang gelombang. Laser dan IPL dengan panjang gelombang pendek efektif untuk lesi hiperpigmentasi superfisial. Sedangkan lesi hiperpigmentasi dermal dan campuran lebih merespons terhadap laser dengan panjang gelombang yang lebih panjang. Pemilihan parameter laser serta persiapan sebelum dan setelah tindakan yang tepat dapat mengurangi risiko efek samping.   With the rapid evolution of technology, laser and intense pulsed light (IPL) have become one of the modalities of choice for hyperpigmentation therapy. The depth of laser beam penetration increases with increasing wavelength. Laser and IPL with short wavelength are effective to treat superficial hyperpigmentations. While dermal and mixed type hyperpigmentations have better response towards lasers with longer wavelength. Accurate laser parameter choice and good pre and post procedural preparations reduce the risk of side effects.
Laki-Laki yang Berhubungan Seksual dengan Laki-Laki (LSL) pada Penderita HIV dan Sifilis Sekunder: Laporan Kasus Ida Ayu Cintya Pradnyandari; Anak Agung Candra Wahyuni; Putu Dyah Ayu Saraswati
Cermin Dunia Kedokteran Vol 51 No 5 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i5.987

Abstract

The incidence of sexually transmitted infections in man who have sex with man (MSM) is increased among human immunodeficiency virus (HIV) patients. HIV and syphilis are two sexually transmitted diseases that frequently interact and modify the symptoms and signs of the disease. A case of a 27-year-old male with generalized multiple erythematous plaques including palms and soles since 4 days ago was reported. The patient has been diagnosed with HIV since 2017. The patient is sexually active with a male sex partner and rarely uses condoms. Diagnosis of syphilis is made based on anamnesis, physical examination, and laboratory tests. The treatment was benzathine penicillin G 2.4 million units in 3 doses. The combination of HIV and syphilis needs longer therapy and requires serological follow-up for up to 24 months.
The Psychophysiological Link Between Chronic Stress and Accelerated Skin Aging: A Comprehensive Literature Review Edward Edwin; Putu Dyah Ayu Saraswati; Ariel Ekaputra; Dana Parama Julius; Ni Made Wiliantari
Jurnal Riset Multidisiplin Edukasi Vol. 2 No. 10 (2025): Jurnal Riset Multidisiplin Edukasi (Edisi Oktober 2025)
Publisher : PT. Hasba Edukasi Mandiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71282/jurmie.v2i10.1074

Abstract

Chronic psychological stress has emerged as a significant but often overlooked factor contributing to premature skin aging. Beyond its well-known systemic effects, sustained stress disrupts the delicate neuroendocrine–immune balance that maintains skin homeostasis. Elevated cortisol and catecholamine levels impair collagen synthesis, increase oxidative stress, and compromise epidermal barrier integrity, thereby accelerating wrinkle formation, dehydration, and loss of elasticity. Moreover, psychoneuroimmunologic pathways involving the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic activation induce chronic low-grade inflammation and telomere shortening, further promoting cellular senescence in dermal fibroblasts. This review synthesizes evidence from dermatologic, neuroscientific, and psychosomatic research to elucidate the mechanisms linking chronic stress and skin aging. Mind–body interventions such as mindfulness, yoga, and cognitive-behavioral therapy have shown potential to modulate cortisol levels and improve skin parameters, highlighting the clinical value of integrative psychodermatology. Understanding this mind–skin connection may inform novel strategies for both aesthetic and therapeutic dermatology by addressing psychological well-being as a core determinant of cutaneous youth and resilience.
Laki-Laki yang Berhubungan Seksual dengan Laki-Laki (LSL) pada Penderita HIV dan Sifilis Sekunder: Laporan Kasus Ida Ayu Cintya Pradnyandari; Anak Agung Candra Wahyuni; Putu Dyah Ayu Saraswati
Cermin Dunia Kedokteran Vol 51 No 5 (2024): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i5.987

Abstract

The incidence of sexually transmitted infections in man who have sex with man (MSM) is increased among human immunodeficiency virus (HIV) patients. HIV and syphilis are two sexually transmitted diseases that frequently interact and modify the symptoms and signs of the disease. A case of a 27-year-old male with generalized multiple erythematous plaques including palms and soles since 4 days ago was reported. The patient has been diagnosed with HIV since 2017. The patient is sexually active with a male sex partner and rarely uses condoms. Diagnosis of syphilis is made based on anamnesis, physical examination, and laboratory tests. The treatment was benzathine penicillin G 2.4 million units in 3 doses. The combination of HIV and syphilis needs longer therapy and requires serological follow-up for up to 24 months.
Co-Authors Anak Agung Candra Wahyuni Ariel Ekaputra Dana Parama Julius Edward Edwin Firly Clarissa Suyanto Ida Ayu Cintya Pradnyandari Ida Ayu Cintya Pradnyandari Ni Made Wiliantari