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Muhammad Faza Soelaeman
Faculty of Medicine, University of Indonesia
Health Professions Medicine & Pharmacology Public Health

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Risk Factors for Community-acquired Pneumonia among Children Under-five Years in Asia: A Systematic Review of Observational Studies Muhammad Faza Soelaeman; Johan Cahyadirga
Cermin Dunia Kedokteran Vol 50 No 9 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i9.841

Abstract

Background: Pneumonia is the leading cause of death among less than 5 year-old children worldwide, mainly in Asia in the form of community-acquired pneumonia. As primary prevention is considered crucial in combating the disease, risk factors need to be analyzed. Methods: Based on the PRISMA guidelines, observational studies were explored systematically by the PubMed MEDLINE database with inclusion and exclusion criteria. The studies retrieved are then assessed with the STROBE method.  Results and Discussion: A total of 8 studies were included, with total participants of 16.862 children. STROBE score results range from 12.2 to 19.6. Several risk factors were associated with pneumonia and risk factor; the highest odds ratio are daytime abnormal behavior (OR: 11.06, 95% CI: 1.51-81.26, p=0.018), asthma diagnosis (OR: 5.85, 95% CI: 4.83–7.08), poor economic status (OR = 4.95, 95% CI: 2.38 to 10.28, p<0.05), and smoke-related cooking process (OR = 3.97, 95% CI: 2.00-7.88, p<0.05). Conclusion: The most associated host risk factor was health-related conditions while the most associated environmental risk factor was the smoke-related environment. Daytime abnormal behavior, the risk factor with the highest odds ratio.   Latar Belakang: Pneumonia adalah penyebab kematian nomor satu pada anak usia di bawah 5 tahun di seluruh dunia, terutama di Asia, dalam bentuk community-acquired pneumonia. Pencegahan primer penyakit ini sangat penting; Oleh karena itu, perlu dilakukan analisis faktor risiko pneumonia pada anak usia di bawah 5 tahun. Metode: Berdasarkan pedoman PRISMA, tinjauan literatur untuk studi observasional dilakukan melalui database PubMed MEDLINE dengan kriteria inklusi dan eksklusi yang telah ditetapkan. Studi yang diperoleh dinilai menggunakan  metode STROBE. Sebanyak 8 penelitian memenuhi kriteria dengan total subjek 16.862 anak. Hasil: Skor STROBE berkisar antara 12,2 hingga 19,6. Beberapa faktor risiko yang berhubungan dengan pneumonia; faktor risiko dengan odds ratio tertinggi adalah perilaku abnormal di siang hari (OR: 11,06; 95% CI: 1,51-81,26; p=0,018), asma (OR: 5,85; 95% CI: 4,83-7,08), status ekonomi buruk (OR=4,95; 95% CI: 2,38-10,28; p<0,05), dan proses memasak yang menghasilkan asap (OR=3,97; 95% CI: 2,00-7,88; p<0,05). Simpulan: Faktor risiko yang paling banyak dikaitkan adalah kondisi kesehatan subjek, sedangkan faktor risiko lingkungan yang paling banyak dibahas adalah lingkungan yang berhubungan dengan asap. Perilaku abnormal di siang hari yang merupakan faktor risiko dengan odds ratio tertinggi.
Risk Factor of Child Diarrhea in Indonesia: A Systematic Review Muhammad Faza Soelaeman; Fabiola Cathleen; Christine Lieana
Cermin Dunia Kedokteran Vol 50 No 11 (2023): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i11.811

Abstract

Bakcground: Diarrhea is the leading cause of death among children worldwide, including in Indonesia. However, there is no scientific research on the most common risk factors for diarrhea among children in Indonesia. A systematic literature review was conducted to highlight the most predisposing risk factors of diarrhea based on the epidemiological triangle, in order to improve preventive measures by society to reduce the incidence of childhood diarrhea. Methods: A systematic review of observational studies without limitation of year of publication was performed in 2023 based on PRISMA protocol. Results: A total of 2607 studies were identified from the Pubmed database, only 9 studies were extracted and assessed using the STROBE method. The risk factors were divided into 3 categories: environmental, host and other, to follow the rule of the epidemiologic triangle of disease. The highest odds ratios were found for the factor "child defecation in open places" (OR=10.47) from the environmental category and for the factor "child eating by hand" (OR=5.6) from the host category. Lower maternal education from the host category was also influential (OR=1.52). Conclusion: Improper public disposal of child feces, child behavior of eating with hand and low maternal education are the most significant contributing risk factors of child diarrhea in Indonesia.
Risk Factor of Child Diarrhea in Indonesia: A Systematic Review Muhammad Faza Soelaeman; Fabiola Cathleen; Christine Lieana
Cermin Dunia Kedokteran Vol 50 No 11 (2023): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i11.811

Abstract

Bakcground: Diarrhea is the leading cause of death among children worldwide, including in Indonesia. However, there is no scientific research on the most common risk factors for diarrhea among children in Indonesia. A systematic literature review was conducted to highlight the most predisposing risk factors of diarrhea based on the epidemiological triangle, in order to improve preventive measures by society to reduce the incidence of childhood diarrhea. Methods: A systematic review of observational studies without limitation of year of publication was performed in 2023 based on PRISMA protocol. Results: A total of 2607 studies were identified from the Pubmed database, only 9 studies were extracted and assessed using the STROBE method. The risk factors were divided into 3 categories: environmental, host and other, to follow the rule of the epidemiologic triangle of disease. The highest odds ratios were found for the factor "child defecation in open places" (OR=10.47) from the environmental category and for the factor "child eating by hand" (OR=5.6) from the host category. Lower maternal education from the host category was also influential (OR=1.52). Conclusion: Improper public disposal of child feces, child behavior of eating with hand and low maternal education are the most significant contributing risk factors of child diarrhea in Indonesia.
Risk Factors for Community-acquired Pneumonia among Children Under-five Years in Asia: A Systematic Review of Observational Studies Muhammad Faza Soelaeman; Johan Cahyadirga
Cermin Dunia Kedokteran Vol 50 No 9 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i9.841

Abstract

Background: Pneumonia is the leading cause of death among less than 5 year-old children worldwide, mainly in Asia in the form of community-acquired pneumonia. As primary prevention is considered crucial in combating the disease, risk factors need to be analyzed. Methods: Based on the PRISMA guidelines, observational studies were explored systematically by the PubMed MEDLINE database with inclusion and exclusion criteria. The studies retrieved are then assessed with the STROBE method.  Results and Discussion: A total of 8 studies were included, with total participants of 16.862 children. STROBE score results range from 12.2 to 19.6. Several risk factors were associated with pneumonia and risk factor; the highest odds ratio are daytime abnormal behavior (OR: 11.06, 95% CI: 1.51-81.26, p=0.018), asthma diagnosis (OR: 5.85, 95% CI: 4.83–7.08), poor economic status (OR = 4.95, 95% CI: 2.38 to 10.28, p<0.05), and smoke-related cooking process (OR = 3.97, 95% CI: 2.00-7.88, p<0.05). Conclusion: The most associated host risk factor was health-related conditions while the most associated environmental risk factor was the smoke-related environment. Daytime abnormal behavior, the risk factor with the highest odds ratio.   Latar Belakang: Pneumonia adalah penyebab kematian nomor satu pada anak usia di bawah 5 tahun di seluruh dunia, terutama di Asia, dalam bentuk community-acquired pneumonia. Pencegahan primer penyakit ini sangat penting; Oleh karena itu, perlu dilakukan analisis faktor risiko pneumonia pada anak usia di bawah 5 tahun. Metode: Berdasarkan pedoman PRISMA, tinjauan literatur untuk studi observasional dilakukan melalui database PubMed MEDLINE dengan kriteria inklusi dan eksklusi yang telah ditetapkan. Studi yang diperoleh dinilai menggunakan  metode STROBE. Sebanyak 8 penelitian memenuhi kriteria dengan total subjek 16.862 anak. Hasil: Skor STROBE berkisar antara 12,2 hingga 19,6. Beberapa faktor risiko yang berhubungan dengan pneumonia; faktor risiko dengan odds ratio tertinggi adalah perilaku abnormal di siang hari (OR: 11,06; 95% CI: 1,51-81,26; p=0,018), asma (OR: 5,85; 95% CI: 4,83-7,08), status ekonomi buruk (OR=4,95; 95% CI: 2,38-10,28; p<0,05), dan proses memasak yang menghasilkan asap (OR=3,97; 95% CI: 2,00-7,88; p<0,05). Simpulan: Faktor risiko yang paling banyak dikaitkan adalah kondisi kesehatan subjek, sedangkan faktor risiko lingkungan yang paling banyak dibahas adalah lingkungan yang berhubungan dengan asap. Perilaku abnormal di siang hari yang merupakan faktor risiko dengan odds ratio tertinggi.
Faktor Prediktif Rekurensi Dini Adenokarsinoma Pankreas Setelah Bedah Reseksi Kuratif: Systematic Review Muhammad Faza Soelaeman; Favian Ariiq Rahmat; Aji Wahyu Wardhana
Cermin Dunia Kedokteran Vol 51 No 6 (2024): Cardiology
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i6.965

Abstract

Introduction: Pancreatic adenocarcinoma stands as one of the most devastating forms of cancer, with a survival rate of less than 5% after 5 years. Despite resection surgery being the only curative option, recurrence occurs in up to 85% of cases. It is crucial to identify factors that can accurately predict the probability of recurrence for more effective management strategies. Method: Following the PRISMA guidelines, a systematic review was carried out by extracting relevant studies from the PubMed MEDLINE database. Results: A total of 1,345 studies were initially identified, and 34 studies were analyzed. A total of thirty-five predictive factors were identified and classified into preoperative and postoperative categories. These factors were be further subdivided into patient characteristics, biomarkers, tumor characteristics, and genetics. The most frequently observed factors were lymph node metastasis, serum CA 19-9 level, and tumor size. Conclusion: Preoperative and postoperative patient characteristics, genetics, biomarkers, and tumor characteristics data can be utilized to predict and implement suitable follow-up strategies aimed at enhancing patient survival rates.
Co-Authors Aji Wahyu Wardhana Christine Lieana Fabiola Cathleen Favian Ariiq Rahmat Johan Cahyadirga