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All Journal MDJ (Makassar Dental Journal)
Ni Putu Tania Chintya Dewi Karima
Unit Kesehatan, Politeknik Transportasi Darat Bali, Denpasar, Bali, Indonesia
Dentistry

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The relationship of Streptococcus mutans spaP gene presence to dental caries severity on children in Denpasar City: Hubungan keberadaan gen spaP Streptococcus mutans terhadap tingkat keparahan karies gigi anak di Kota Denpasar Ni Putu Tania Chintya Dewi Karima
Makassar Dental Journal Vol. 12 No. 2 (2023): Volume 12 Issue 2 Agustus 2023
Publisher : Makassar Dental Journal PDGI Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35856/mdj.v12i2.772

Abstract

Oral health problems, especially dental caries, are the most common health problems experienced by children in Indonesia. Streptococcus mutans as the main causative agent of dental caries has the spaP gene which plays a role in the initial process of bacterial invasion. Performing PCR on children's dental plaque samples can determine the presence of the genes spaP S.mutans. Then, the existing data were statistically analyzed using the logistic regression method to assess the relationship of the genes spaP S.mutans to the severity of dental caries. From the research results, 54 samples contained the spaP gene of S.mutans. The prevalence of gene S.mutans spaP in dental plaque in children aged 3-5 years in Denpasar City was 69.2%. The statistical ana-lysis results revealed that the spaP gene of S.mutans (p=0.016) had a p<0.05. It is concluded that the variable presence of the S.mutans spaP had a significant relationship with the severity of dental caries on children aged 3-5 years in Denpasar City.
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