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p-Index From 2021 - 2026
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All Journal World Nutrition Journal
Yohanessa Wulandari
Faculty of Medicine University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia
Medicine & Pharmacology Public Health

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Effect of oral iron supplementation on functional capacity in heart failure patients: Evidence Based Case Report Gabriela Widyakarin Tjandra; Yohanessa Wulandari
World Nutrition Journal Vol. 7 No. 01 (2023): Volume 07 Issue 1, August 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/10.25220/WNJ.V07.i1.0003

Abstract

Introduction: Cardiovascular disease is the leading cause of mortality worldwide. Heart failure (HF) accounts for 13.4% of deaths and reduces the quality of life of patients. Iron- deficiency is a common condition found in heart failure patients, often occurs due to decrease in iron intake, absorption, and chronic inflammation. Oral iron supplementation is a low-cost and easy alternative for iron-deficiency management in heart failure patients. Method: Literature search was conducted using advanced searching in three large databases: PubMed, Cochrane Library, and Google Scholar. MeSH terms, advanced search and eligibility criteria were used for title and abstract screening after removing duplicates. Critical assessment tools and levels of evidence of the final articles are based on the Oxford Center for Evidence-Based Medicine. Results: Two systematic reviews and meta-analyses and two RCTs met the PICO and eligibility criteria that had been set. Two systematic reviews and meta-analyses found that oral iron supplementation did not improve the functional capacity of heart failure patients, while the two RCTs found an improvement in functional capacity in heart failure patients who received oral iron supplementation. Conclusion: Based on critical reviews that have been carried out, currently we do not recommend oral iron supplementation in heart failure patients. Further research may potentially provide different recommendations as oral iron therapy evolves.
Effect of probiotic supplementation on wound healing in postoperative patients: A case report and literature review Cut Thalya Alissya Rahma; Yohanessa Wulandari
World Nutrition Journal Vol. 7 No. 01 (2023): Volume 07 Issue 1, August 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/10.25220/WNJ.V07.i1.0012

Abstract

Background: Delayed wound healing, particularly in chronic wounds, is a significant global public health issue. The World Health Organization (WHO) reports that over 6 million people in the United States experience delayed wound healing annually, resulting in a healthcare cost of $25 billion USD. Probiotics, known for their anti-inflammatory properties, have potential in influencing skin immunity by facilitating the transfer of cytokines and immune cells from Peyer's patches to the skin. Nevertheless, the precise impact of probiotics on postoperative wound healing remains an area with limited research. Objective: Determine the effectiveness of probiotic supplements in wound healing in patients with surgical wounds Method: Literature search is done by advanced searching on Pubmed, Cochrane, Scopus, and EBSCOhost with eligibility criteria determined by the author. Results: There were three articles relevant to clinical questions and eligibility criteria that had been established, consisting of one systematic review article from the randomized controlled trial (RCT) study and two RCT articles. The SR/MA article includes good-quality RCT studies. The SR/MA article showed insignificant results on the effect of probiotic administration on healing. The RCT article showed significant results on the effect of probiotics on surgical wound healing, but the confidence level was low in one of the articles. Conclusion: Probiotic supplementation on wound healing in postoperative patients is not conclusive. This can be affected by the type of probiotic strain, dosage, duration of administration, and location of the surgical wound.
Co-Authors Cut Thalya Alissya Rahma Gabriela Widyakarin Tjandra