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Marek Nalos
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Medicine & Pharmacology Public Health

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Lactate – from villain to guardian Marek Nalos
World Nutrition Journal Vol. 7 No. S1 (2023): Selected conference proceedings of the Nutri Symposium 2023
Publisher : Indonesian Nutrition Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25220/V07.S1.0009

Abstract

Elevated plasma lactate level is a useful warning sign in patients presenting with a variety of critical illnesses. Our understanding of hyperlactatemia, however, has improved and we can no longer associate lactate itself with any harmful effects. Lactate is a crucial intracellular buffer, and a central molecule in the interorgan exchange of carbon and redox potential. While lactate levels correlate with severity of acidaemia in shock there is little evidence to support the commonly held view that its origin is mainly secondary to anaerobic metabolism because of reduced tissue oxygen delivery.
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