Yeti Rusmiati Hasanah
Department of Chemical Engineering, Faculty of Engineering and Science, Universitas Muhammadiyah Purwokerto, Indonesia

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Effect of Drying Method on Antioxidant Activity and Total Flavonoid Content of Java Tea Crude Drug (Orthosiphon aristatus) Daffa Purnomo; Alvina Yulianti Putri; Haikal Muhammad Hisyam; Rizka Rimatunnisa; Dania Regita Indriani; Pasca Ryan Adinda; Yeti Rusmiati Hasanah; Alwani Hamad
Research in Chemical Engineering Vol. 2 No. 1 (2023): March
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/rice.v2i1.87

Abstract

Java tea (Orthoshipon aristatus) is a medicinal plant with antioxidant properties due to its polyphenols, flavonoids, phenolic acids, terpenoids, and sinensetin content. Numerous diseases, including hepatitis, diabetes, hypertension, and others, are commonly treated with Java tea. These bioactive compounds are unstable and readily degraded by oxygen, heat, and light. Inappropriate dehydration techniques may compromise the quality of the bioactive compounds in herbal Java tea crude drugs by damaging the bioactive compounds. Consequently, this study aims to determine the effect of various drying methods on the antioxidant activity and Total Flavonoid Content (TPC) of the crude drug of Java tea. In addition, the physical properties, including water content and hygroscopicity, are investigated. The method employs cabinet drying at 30 and 70 degrees Celsius, infrared drying, and sun drying. The results demonstrated that the crude drug dried in a cabinet at 30oC had the maximum flavonoid content (61.03±5.35mg QE/g) and moisture content (15.12±0.27%). The antioxidant activity of DPPH free radical scavenging and Ferri Reduction Antioxidant Power (FRAP) of Java tea from infrared drying was lower than other drying methods. All samples were non-hygroscopic powders. Consequently, the dehydration method significantly affects the antioxidant activity, TFC levels, and physical properties of the crude drug of Java tea.
Effect of Drying Method on Antioxidant Activity and Total Flavonoid Content of Java Tea Crude Drug (Orthosiphon aristatus) Daffa Purnomo; Alvina Yulianti Putri; Haikal Muhammad Hisyam; Rizka Rimatunnisa; Dania Regita Indriani; Pasca Ryan Adinda; Yeti Rusmiati Hasanah; Alwani Hamad
Research in Chemical Engineering Vol. 2 No. 1 (2023): Research in Chemical Engineering
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/rice.v2i1.87

Abstract

Java tea (Orthoshipon aristatus) is a medicinal plant with antioxidant properties due to its polyphenols, flavonoids, phenolic acids, terpenoids, and sinensetin content. Numerous diseases, including hepatitis, diabetes, hypertension, and others, are commonly treated with Java tea. These bioactive compounds are unstable and readily degraded by oxygen, heat, and light. Inappropriate dehydration techniques may compromise the quality of the bioactive compounds in herbal Java tea crude drugs by damaging the bioactive compounds. Consequently, this study aims to determine the effect of various drying methods on the antioxidant activity and Total Flavonoid Content (TPC) of the crude drug of Java tea. In addition, the physical properties, including water content and hygroscopicity, are investigated. The method employs cabinet drying at 30 and 70 degrees Celsius, infrared drying, and sun drying. The results demonstrated that the crude drug dried in a cabinet at 30oC had the maximum flavonoid content (61.03±5.35mg QE/g) and moisture content (15.12±0.27%). The antioxidant activity of DPPH free radical scavenging and Ferri Reduction Antioxidant Power (FRAP) of Java tea from infrared drying was lower than other drying methods. All samples were non-hygroscopic powders. Consequently, the dehydration method significantly affects the antioxidant activity, TFC levels, and physical properties of the crude drug of Java tea.
Drying Methods Affecting the Antioxidant Activity of Turmeric Crude Drug Anila Wirantika; Idda Nuriya Rahma; Raafi Akbar Putra; Devita Almayda; Diah Ayu Kusumawati; Muhammad Agil Nur Fauzan; Yeti Rusmiati Hasanah; Afwa Hayuningtyas; Pinyapat Jitphongsaikul; Alwani Hamad
Research in Chemical Engineering Vol. 2 No. 2 (2023): Research in Chemical Engineering
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/rice.v2i2.111

Abstract

Turmeric is commonly a spice with many benefits in improving health, including antioxidants, anti-inflammatory and antimicrobial properties. The preparation of turmeric crude drug usually uses conventional sun drying. However, the quality of crude drugs is uncontrollable. The alternative using a modern drying process may affect the antioxidant properties of the final crude drug. This research aims to investigate the effect of drying methods (cabinet drying at 30oC and 70oC, infrared (IR), and conventional sun drying) on the antioxidant activity of turmeric crude drugs. The moisture content and its chemical compounds, including Total Phenolic Content (TPC) and Total Flavonoid Content (TFC), were also investigated. Antioxidant activity was measured using DPPH free radical scavenging and Feri Reducing Antioxidant Power (FRAP) method. The results showed that the moisture content of dried turmeric samples from cabinet drying at 70 C and sun drying was less than 10%. TPC of all dried turmeric from modern drying methods was significantly higher than conventional sun drying and the same as TFC results, except for the sample from the IR method. The antioxidant activity of dried curcumin from IR drying was significantly higher than that of another sample in the FRAP method. However, the higher antioxidant of dried turmeric using the DPPH free radical scavenging showed in dried turmeric from cabinet drying at 70 C and sun drying. The results of the antioxidant activity of the dried turmeric crude drug did not correlate with the TPC and TFC data as predicted using Pearson’s Correlation. Thus, it can be concluded that the drying methods influenced the antioxidant activity of turmeric crude drug, and it did not correlate with phenolic and flavonoid content.
Utilization of Coffee Grounds as an Adsorbent in Reducing the Levels of Naphthol Dyes of Weaving Industry Wastewater Adlina Fitry; Neni Damajanti; Yeti Rusmiati Hasanah
Research in Chemical Engineering Vol. 3 No. 1 (2024): Research in Chemical Engineering
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/rice.v3i1.174

Abstract

Naphthol dye is one of the synthetic dyes contained in weaving industry waste. One method that can be used to reduce the disadvantageous effects of these substances is by adsorption using activated charcoal adsorbent from coffee grounds. This research aims to determine the character of activated charcoal from coffee grounds and the effect of adsorbent dosage and stirring time on the adsorption of naphthol dye levels. Making activated charcoal from coffee grounds goes through 3 stages, namely the dehydration stage, carbonization stage at 350 oC for 3.5 hours, and activation stage using a 0.1 M HCl activator for 48 hours. The characterization of activated charcoal obtained complies with SNI 06-3730-1995 with results of water content of 3.74%, ash content of 2.12%, and iodine adsorption capacity of 758.29 mg/g, and functional group testing was carried out by varying the adsorbent dosage at 0.125; 0.250; 0.500; 0.750; 1 g (per 100 mL sample) and stirring time for 10; 20; 30; 40; 50 minutes. From the research results, it was obtained the best adsorbent dose and mixing time were 0.5 g and 40 minutes with adsorption efficiency of 98.68% and 99.63%.
Extraction and Characterization of Pectin from Snake Fruit Peel via Maceration Raafi Akbar Putra Purnomo; Yeti Rusmiati Hasanah; Neni Damajanti
Research in Chemical Engineering Vol. 3 No. 2 (2024): Research in Chemical Engineering
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/rice.v3i2.210

Abstract

The high consumption of fruit flesh from the snake fruit is not in line with the utilization of fruit peels, which are often considered organic waste that goes to waste. The lack of optimal utilization of fruit peels as organic waste can open up opportunities to develop other alternatives, such as using fruit peels as a source of pectin. The extraction of pectin from fruit peels is carried out using the maceration extraction method with citric acid as the solvent. This research aims to determine the effect of the solvent material ratio and solvent concentration, as well as to understand the characteristics of the resulting pectin product. The results of this study indicate that among the variations in the ratio of materials and solvents, the highest %yield was achieved at a ratio of 1:40 (gr/mL) with a %yield value of 13.15%. In the variations of solvent concentration, the highest pectin %yield was at a concentration of 10% with a %yield value of 17.5%. The characteristics of the produced pectin were the highest equivalent weight of 114.94 mg, the highest methoxyl content of 9.92%, and the highest galacturonic acid content of 1063.04%. Functional group analysis using FTIR showed the presence of the O-H functional group at a wavelength of 3255 cm-1, the aliphatic C-H functional group at a wavelength of 2808 cm-1, the carboxyl (C=O) functional group at 1838 cm-1, and the methyl C-H functional group at a wavelength of 1442 cm-1. Therefore, the best research results were found at 1:40 and a solvent concentration of 10% with the highest %yield, equivalent weight, methoxyl content, and galacturonic acid content