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All Journal Jurnal Gizi Klinik Indonesia Strada Jurnal Ilmiah Kesehatan (SJIK)
Susanti, Yuyun Erlina
Fakultas Kesehatan Masyarakat, Universitas Airlangga Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Pengaruh ekstrak melon terhadap kadar HbCO pada tikus Wistar jantan yang dipapar asap rokok Yuyun Erlina Susanti; Bambang Wirjatmadi; Merryana Adriani
Jurnal Gizi Klinik Indonesia Vol 13, No 3 (2017): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17832

Abstract

Background: Smoking is something that is usual for most Indonesian society, especially adult males. According to Riskesdas, smoking behavior of the population trends to increase. A previous study suggested that exposure to cigarette smoke produce CO bond to hemoglobin. Melon (Cucumis melo) contains antioxidants that prevent tissue damage.Objective: Analyze differences in levels HbCO Wistar male rats in treated and untreated extracts of melon.Method: The research was a laboratory experiment with the post test control group design and complete random design. The subjects were 25 male Wistar rats aged 3 months. Subjects were divided into 5 groups and each group received treatment for 28 days. Data of level HbCO was collected and analyzed by Anova One Way test at 95% confidence level.Results: The results showed a difference between the average levels of HbCO male Wistar rats (p value=0,000) treated and untreated extracts of melon.Conclusion: Melon extracts effect on decreasing the levels of HbCO due to exposure to cigarette smoke. There were differences in levels of male Wistar rats HbCO on treated and untreated extracts of melon and be given at a dose of 250 IU/day.
GAMBARAN BERAT BADAN, KADAR HEMOGLOBIN, DAN KADAR HbCO PADA TIKUS GALUR WISTAR JANTAN ( Rattus Novergicus) YANG DIPAPAR ASAP ROKOK Yuyun Erlina Susanti
STRADA : Jurnal Ilmiah Kesehatan Vol. 5 No. 2 (2016): November
Publisher : Universitas STRADA Indonesia

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Abstract

Smoking is something that is habit for most Indonesian society, especially adult males. Smoking behavior of the population tends to increase. The exposure of cigarette smoke affects weight, binds Haemoglobin and produce CO bond in haemoglobin. The aim of this study was to analyze the difference of weight, Hemoglobin and Carboxyhemoglobin concentration in male Wistar rats. The study was a laboratory experimental design, using Post Test Control Group Design Research and RAL method (Complete Randomize Design). The sampel in this study were 10 male Wistar rats aged 3 months. The subjects were divided into 2 groups and each group received treatment for 28 days. Data of level HbCO was collected and analyzed by Anova One Way test at 95% confide nce level using SPSS version 16.0. The results showed significant difference in average Hb and HbCO concentration (p-value<0,05) male Wistar rats.The effect of cigarette smole exposured can lead to weight loss, a decrease in hemoglobin and increase Carboxyhemoglobin. Thus it is important area without cigarette smoke to avoid these impacts
Co-Authors Bambang Wirjatmadi Merryana Adriani