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All Journal Collaborative Medical Journal (CMJ) The International Science of Health Journal Jurnal Ventilator: Jurnal Riset Ilmu Kesehatan dan Keperawatan
Lasmaria Flora Roslinda Silaen
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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PENGARUH GEL PUTIH TELUR BEBEK TERHADAP PENYEMBUHAN LUKA INSISI PADA MENCIT (Mus musculus) Mahendra Mahendra; Abdul Karim; Arman Ismail; Lasmaria Flora Roslinda Silaen
Collaborative Medical Journal Vol 6 No 2 (2023): Mei
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/cmj.v6i2.3840

Abstract

Luka pada kulit merupakan masalah kesehatan yang umum terjadi dan dapat disebabkan oleh berbagai faktor seperti cedera atau operasi. Kulit merupakan pertahanan pertama tubuh terhadap mikroorganisme dan zat-zat kimia, sehingga luka pada kulit dapat menyebabkan kerusakan pada jaringan. Prevalensi luka di Indonesia meningkat dari tahun 2012 7,5% menjadi 8,2% pada tahun 2013. Pengobatan tradisional masih banyak digunakan oleh masyarakat, dan telur memiliki potensi sebagai alternatif pengobatan yang efektif karena kaya akan protein dan asam amino yang diperlukan untuk membentuk jaringan baru dan mempercepat proses penyembuhan. Berdasarkan penelusuran di PubMed belum ada penelitian mengenai hubungan putih telur bebek terhadap penyembuhan luka insisi. Tujuan dari penelitian ini adalah menganalisis pengaruh gel putih telur bebek terhadap penyembuhan luka insisi pada mencit. Metode peenelitian ini adalah penelitian eksperimental dengan rancangan Postestt only with Control Group dengan dua puluh ekor mencit dibagi menjadi empat kelompok yaitu kelompok kontrol positif menggunakan povidone iodine, kontrol negatif mengunakan basis gel dan kelompok perlakuan 1 dengan gel telur bebek 10% dan perlakuan 2 gel telur bebek 20%. Perlakuan berupa inisis pada punggung mencit dengan Panjang 1cm dengan kedalaman 0,2cm dan pengukuran sisa Panjang luka 2 hari sekali menggunakan jangka sorong pda hari ke-3, 5 dan 7. Hasil dari penelitian ini didapatkan nilai p<0,05 yang menunjukkan bahwa gel putih telur bebek dengan konsentrasi 10% dan 20% efektif mempercepat penyembuhan luka insisi pada mencit. Gel putih telur bebek konsentrasi 20% memiliki efektivitas paling adekuat terhadap penyembuhan luka insisi pada mencit
Cases Report On The Management Of Hospital Acquired Pneumonia In Ischemia Stroke Patients Lasmaria Flora Roslinda Silaen
The International Science of Health Journal Vol. 2 No. 3 (2024): September: The International Science of Health Journal
Publisher : Sekolah Tinggi Ilmu Kesehatan Kesdam IV, Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ishel.v2i3.1348

Abstract

Pneumonia is defined as acute inflammation of the pulmonary parenchyma caused by bacteria, viruses, fungi, parasites. Nosocomial pneumonia (Hospital Acquired Pneumonia) is pneumonia that is acquired while being hospitalized, at least after 48 hours of treatment and not in the incubation period. The average incidence of HAP is 5-15 per 1000 residents of hospital cases, while in the intensive care unit it is around 25%, where 70-80% of episodes of pneumomia occur when using a ventilator. Sentry Antimicrobial surveillance research found that 80% of nosocomial pneumonia bacteria are caused by six pathogenic bacteria, namely Staphilococcus aureus, Pseudomonas aeruginosa, Klebsiella species, E coli, Acinetobacter species and Enterobacter species. It was reported that a 68-year-old woman came to the emergency room four days before entering the hospital with a sudden decrease in consciousness while resting. Patients admitted with GCS 10 were treated in the room with a diagnosis of ischemic recurrent stroke + type 2 DM + Hypertension + Anemia. After eleven days of being treated in the room, the patient experienced shortness of breath, decreased saturation and GCS was decreasing, diagnosed with ischemic stroke + HAP + respiratory failure, intubated and connected to a ventilator in the ICU.
Efek Kava (Piper Methysticum) Sebagai Anestesi Lasmaria Flora Roslinda Silaen; Matdhika Sakti; Ferianto Ferianto
Jurnal Ventilator Vol. 3 No. 1 (2025): Jurnal Ventilator
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/ventilator.v3i1.1737

Abstract

Kava (Piper Methysticum) is a plant traditionally used in the South Pacific for its sedative and anxiolytic effects. Its active compounds, kavalactones, are known to have potential as natural anesthetics, with a mechanism of action similar to benzodiazepines and general anesthetics. This study aims to evaluate the effectiveness of Kava as an anesthetic through a systematic literature review and meta-analysis. Literature searches were conducted in PubMed, Scopus, and Cochrane Library using relevant keywords. Meta-analysis results indicate that Kava significantly enhances anesthetic effects compared to placebo, primarily through modulation of GABA-A receptors. However, further research is needed to determine the optimal dosage and long-term safety.
Co-Authors Abdul Karim Arman Ismail Ferianto Ferianto Mahendra Mahendra Matdhika Sakti